It's not just surgical intervention but post-traumatic osteoarthritis (PTOA) from joint trauma that's a big red flag. And it starts with some type of injury to a joint - usually a torn or partially torn ligament, tendon, cartilage or even a fracture that initiates a degenerative process. A signficantly torn meniscus is a big one that invariably leads to OA whether it's surgically repaired or not. And OA of knee, ankle & hip are the bad ones for runners and those doing other high-impact activities (13 million adults age 60 & older have clinically diagnosed OA of just the knee!).
I have ankle, knee & hip OA. Several years ago during a sprint finish of a 5k race, I completely ruptured the Posterior Tibial Tendon of my ankle - it literally exploded as I engaged in a full uphill sprint finish dropping me like a lead balloon! ? (this was bad and I've had some pretty hard hits from my football days). Surgery was an option but not recommended primarily because of my age (lengthy non-weight bearing recovery) and the fact that with the right rehab I could return to some form of running. Rehab was about 3 months before a return to full running but with a lot of limitations (mileage, intensity, racing, etc.).
But repetitive use of a traumatized joint leads to PTOA. In my case later follow-up radiographs & MRI showed significant degenerative changes within the cartilage between the tibia & talus. Any cartilage degeneration of a joint is bad news for a runner. My foot & ankle surgeon says in the future I'll be needing a complete fusion surgery which is a major procedure with plates, screws and all that fancy hardware. Right now I'm told to let pain be my guide, continue rehab excercises & more non-weightbearing activity.
My knee PTOA (mild) is from a partially torn ACL from my college football days. And I have no idea where my hip OA (also mild) originated from. But it's only one hip with moderate soreness from time & time...nothing compared to the ankle.
Running on replaced joints is probably is not advisable and is just going to wear the parts out more quickly. However, that being said, I know two guys from the master running club I used belong to that continued to run after knee replacements. One, a faster running in his age group, had a torn meniscus about 12 yrs ago that was surgical repaired and he continued on with a pretty heavy training & race schedule. In his 70s, he developed severe PTOA and had a full joint replacement and still runs & races, but much slower now with a pronounced shuffle-step type form. The other guy, in his late 60s, had two partial knee replacements and runs very slowly with the same shuffle step motion. It's almost fast walking with a gliding motion as they're trying to minimize impact forces.
I'd say soft tissue injuries, mild tendon, ligament & muscle strains, and tendinitis type stuff is nothing compared to severe trauma to a joint. Those aforementioned pathologies are manageable with the right rehab & nutrition, IMO. Trauma to the structures of any joint is bad news and will invariably lead to PTOA, and pretty much game over for high-impact activities. So, count your blessings if you haven't had any major trauma to a joint.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488839/