I received dose one of the Pfizer vaccine. AMA.

Did you have to get an antibody test to be eligible for the vaccine?

If not, doesn't that make sense? With such a limited supply of vaccines at the moment, only those most vulnerable (eg those with pre-existing conditions including the elderly and frontline medical workers) who do not already have some level of specific immunity to the virus should be getting the vaccine until there is enough to go around. Obviously, there are some logistical barriers to have to get the antibody test first, but it would allow more benefits with the same amount of vaccine.

runner_hero wrote:

Between 14:15 and 14:30. Current fitness I’d probably only be able to run like 16:00.

If you are young enough to still run 16:00 why were you entitled to receive the vaccine?

Quintus Cassidamius wrote:

Did you have to get an antibody test to be eligible for the vaccine?

If not, doesn't that make sense? With such a limited supply of vaccines at the moment, only those most vulnerable (eg those with pre-existing conditions including the elderly and frontline medical workers) who do not already have some level of specific immunity to the virus should be getting the vaccine until there is enough to go around. Obviously, there are some logistical barriers to have to get the antibody test first, but it would allow more benefits with the same amount of vaccine.

They are asking people who have had Covid not get the vaccine until others get it. They would still like former Covid patients to get it because they don't know how long they will remain resistant....however, the latest study shows that 95% of people still have high levels immunity 6-8 after having it.

mjohnson5 wrote:

[quote]Quintus Cassidamius wrote:

Did you have to get an antibody test to be eligible for the vaccine?

If not, doesn't that make sense? With such a limited supply of vaccines at the moment, only those most vulnerable (eg those with pre-existing conditions including the elderly and frontline medical workers) who do not already have some level of specific immunity to the virus should be getting the vaccine until there is enough to go around. Obviously, there are some logistical barriers to have to get the antibody test first, but it would allow more benefits with the same amount of vaccine.

Yes, they are asking people who have had Covid not get the vaccine until others get it. They would still like former Covid patients to get it because they don't know how long they will remain resistant....however, the latest study shows that 95% of people still have high levels immunity 6-8 months after having it.

its amazing. within days of the vaccine being released, it seems as if more lrc people have had the vaccine than had had covid in the equivalent number of months.

PS that Chinese paper is guesswork - they tested nobody before symptom onset, and therefore any conclusions about stuff before that is pure guesswork. there are any number of other problems, but i will leave the typical 'we didnt know so we guessed and made a model without any actual evidence' syndrome as sufficient.

runner_hero wrote:

Ask me anything.

How'd you get it? Are you a front line worker or something or did you buy your way to the front of the line?

moneytoburn wrote:

runner_hero wrote:

Ask me anything.

How'd you get it? Are you a front line worker or something or did you buy your way to the front of the line?

He didn’t get the vaccine. 1/10

pupil3142 wrote:

its amazing. within days of the vaccine being released, it seems as if more lrc people have had the vaccine than had had covid in the equivalent number of months.

PS that Chinese paper is guesswork - they tested nobody before symptom onset, and therefore any conclusions about stuff before that is pure guesswork. there are any number of other problems, but i will leave the typical 'we didnt know so we guessed and made a model without any actual evidence' syndrome as sufficient.

Given that the viral load declined from the moment of symptom onset, any construction that doesn’t include a pre-symptomatic period requires the virus to suddenly appear in the body at the maximum level the body will see. It means there is no ramping up period where the virus is replicating and increasing the load in the body. While you can debate how much area under the curve belongs to the presymptomatuc period, to state that it is not a significant portion requires us to think that Covid behaves differently than (to my understanding) every infectious agent ever. If someone can demonstrate an infectious agent that has no ramping up period, starts at maximal load and then decreases please let me know and we can see if it is comparable.

runner_hero wrote:

1) I’d really like to not spread it to old people.

2) while my individual risk of dying or having long term consequences from covid is very low I still think it’s better to get the vaccine than the disease.

Jury is still out whether or not you can still spread it after being vaccinated.

Symptomatic positives are highly correlated with transmissibility and the vaccine is highly correlated with no symptomatic positives. While it might not prevent transmission on the exact same level it prevents symptoms (95%) - it is going to have a strong effect.

I am less certain, Irv Weiss an mentioned that there could be a problem to do with the lymphocyte homing cells that might result in the mucosa being unprotected, meaning systemically you are ok, but the parts of the body that are most exposed remain active sources of infection.

I don’t know how much of an issue it will actually be, not sure anybody does, but I wouldn’t make an assumption there.

Irv Weissman md

Yes mucosal immunity is different from traditional adaptive immunity. It's hard to say for sure without big studies - but I would need to see convincing evidence that reducing overall viral load doesn't have a significant effect on duration and amount of transmission. Occams razor and all.

trashcan wrote:

Irv Weissman md

Got the first dose two days ago. Had serious deltoid soreness starting 12 hours after injection that lasted 36 hours and resolved. Much worse than any flu vaccine I’ve had. No other side effects.

Exactly what w/in reason did they tell you about the second shot? When, where, etc...

Did you a sd k questions? Eg. To what degree will that

pair of shots protect you against a new strain of Covid? Did you have to pay?

Do you believe the vaccine will help? How do you feel after her? I'm afraid to bet myself, although the family convinces me that it's worth doing it

bryan evans wrote:

runner_hero wrote:

Ask me anything.

Since the Pfizer vaccine has to be stored at -70C, how could they have possibly injected the actual Pfizer vaccine into you without destroying your muscle tissue? Checkmate libs.

"Even that presents challenges, though — a Pfizer scientist told a CDC advisory council in August that it's not supposed to be opened more than twice a day and needs to be closed within one minute of opening. Once it's thawed, the vaccine can be refrigerated for five days."

It's just stored for the long term at -70 C, after the vaccine can be stored for five days at refrigerated 2-8°C conditions in a liquid form. Think about it like putting your meat or bread in the freezer so it won't spoil, but then taking it out and thawing them when you are ready to eat it.

(read this it's from a non-biased news source too)

So you do think kids with no symptoms are killing people with the virus?

Wow.

Quintus Cassidamius wrote:

Did you have to get an antibody test to be eligible for the vaccine?

If not, doesn't that make sense? With such a limited supply of vaccines at the moment, only those most vulnerable (eg those with pre-existing conditions including the elderly and frontline medical workers) who do not already have some level of specific immunity to the virus should be getting the vaccine until there is enough to go around. Obviously, there are some logistical barriers to have to get the antibody test first, but it would allow more benefits with the same amount of vaccine.

No I didn’t have to take an antibody test. Does it make sense? I’m an immunologist but if you have antibodies to spike proteins whether from infection or vaccine it seems you should be immune. Right now most healthy people are thought to have at least 6 months of immunity post infection. Of course no one knows how long the antibodies last for either infection or vaccine.