My theory is thus:
Thinner(midsole), flatter (drop) shoes load "lower" and are more likely to result in injury to the feet.
Thicker, steeper shoes load "higher" and are more likely to result in injury to the knees/hips/back.
My personal experience: running in "traditional" shoes (moderate thickness, 10mm drop) always had knee trouble, especially patellar tendinitis. Low back tight, occasional sciatica. Feet never hurt.
Changed to training in minimal, zero drop shoes, knee trouble completely disappeared, hips and back felt great. Truly bulletproof from the shins up. But got metatarsal stress fracture (a first for me).
I think I've found a good compromise for myself: training in flats with no more than a 4mm drop. Thin and flat enough to feel "biomechanically correct" from the knees up, while also thick enough to avoid breaking my feet bones.
The trick, of course, is to find the combo that injures YOU the least.