Kenyan 800m Word medallist Kipyegon Bett Suspended After Refusing Drugs Test

685678 wrote:

Sprintgeezer wrote:

You don’t realize it, but bs like you’re talking makes a mockery of the experiences of those of us who have suffered actual racism.

Some day you may understand.

You are so patronizing it's laughable.

Some day you may grow up, and realize that some people have had similar experiences to yours.

Yes i was patronizing. You deserved every bit of it.

You continue to be an embarrassment.

trollism wrote:

El Keniano wrote:

C’mon, man! You really think it’s normal that out of nearly 400 positives, for next to zero to be westerners? Statistically implausible.

https://www.athleticsintegrity.org/downloads/pdfs/knowledge-centre/en/AIU-infographic-All.pdf

I think your attitude is exactly the reason why so many Kenyans are cheats.

You justify their cheating by saying 'evil white people cheat worse so it's ok'.

When the fans and the general Kenyan public think like this, it's hardly going to stop the athletes from doping cause they think they're justified in doing so and then they don't get much criticism back home anyway even if they are busted.

This looks awfully one-sided and you know it. I guarantee you there's someone on PEDs wherever you are in the world, including your local gym, which is why this is so odd . I fully support cheaters getting busted but this reeks of an agenda. Journalists that lurk here should raise this query. Maybe they haven't got around to testing Brits and Aussies yet because of limited resources? But this ... this smells fishier than a fish market.

What's so weird about that? I bett if the situation was reversed and it was the Americans & Brits testing positive like crazy and not the Kenyans, you wouldn't be asking these same questions. ?

I think Renato was asking with respect to your study that you found interesting, that HcT and VO2max can be increased with EPO. In the study, "All subjects agreed to maintain their level of physical activity unchanged throughout the trial period.", so training is both unassessed and unchanged. Here's the original question in full, with many questions related to different training scenarios -- what is the effect of training on these variables in the study you found interesting:

El Keniano, You say nearly 400 and it's one-sided. I don't see anywhere in that info-graphic that the 374 AAFs are only Kenyans or East Africans. Note that an AAF is not yet a suspension or sanction. From these 374 AAFs, I see 48 elite international level cases, 18 suspensions, 11 in Disciplinary tribunal, and 20 referred to CAS (18 of them Russian), 60 investigations in total, 28 of which are closed. Besides the racial makeup of the AIU, what leads you to suspect that Kenya is being unfairly targeted?

El Keniano wrote:

This looks awfully one-sided and you know it. I guarantee you there's someone on PEDs wherever you are in the world, including your local gym, which is why this is so odd . I fully support cheaters getting busted but this reeks of an agenda. Journalists that lurk here should raise this query. Maybe they haven't got around to testing Brits and Aussies yet because of limited resources? But this ... this smells fishier than a fish market.

Japanese are worse wrote:

RACIST!!!

RACIST!!! wrote:

Japanese are worse wrote:

RACIST!!!

Hi Coevett.

Sprintgeezer wrote:

685678 wrote:

You are so patronizing it's laughable.

Some day you may grow up, and realize that some people have had similar experiences to yours.

Yes i was patronizing. You deserved every bit of it.

You continue to be an embarrassment.

haha look who's talking. You've been embarrassing yourself on here for years.

Japanese are worse wrote:

http://athletics.co.ke/moeno-nakamura-fails-drug-test/

Hey...this isn't so good since Japan is hosting the upcoming Olympics. ?

685678 wrote:

RACIST!!! wrote:

RACIST!!!

Hi Coevett.

Hi vivalarepublica!

El Keniano wrote:

m!ndweak wrote:

so who are the next two to be reveled? why are we being left in the dark? el k...you claim your a hobby jogger kenyan...YOU SHOULD BE THE BOOTS on the ground...who is being banned next!?!?!?!

Why can't you wait for the official announcement along with everyone else? Don't you have anything going on in your obviously very exciting life to keep you busy until then?

well im slightly trying to rial you up chief....and at the same time since you claim your not from essex, but you claim you are from the affluent neighborhood of Karen, nairobi, and claim to know all the ins and outs of the top kenyan runners. like how you know so much about the brothers, the correct ages, bowel movements, whereabouts, where they buy tea, and how much potatoes cost....i just figured you WOULD know who the next two kenyans names are...and an excuse for them as well :P

got to love that.....so nice we all have rekrunner to tell us what Renato is thinking

its the same annoying stupid rant. "but but but they arent trained"

and if the study is with trained runners, then you and the other deniers have this to say "but but but what about elite trained runners?"

let me ask YOU this rek, please if you CAN explain how a DRUG, created to trick the HUMAN body into making more EPO than was EVER natural for the body.....works for 99.9% untrained and trained people, but somehow some f*cking magically thing keeps it from working on .1% of the WORLDS population?

can you please come up with some concrete logical with PROOF on how that is besides your interpritation on what you THINK renato is talking about.

found this, pretty classic....you know with all those people who talked sh*t about how my dates where sooo off

"Successful cloning of the EPO gene in 1983 [5] allowed for the large-scale production of rhEPO and its subsequent clinical use"

and this is what i have been asking recently to you and all the OTHER so called EPO experts on here. natural EPO has a set molecular structure. rhEPO has DIFFERENT structures, thus would cause them to bind to DIFFERENT protein receptors in the CELLS or am i way off?

"Epoetins alfa and beta, both produced by Chinese hamster ovary cells, have minor structural differences but the same physiological effects"

well this was 2008 study, that LAST one i posted was from 2016? and it said there was NOTICEABLE mitochondrial CHANGES

scroll down to page 7, and see what i mean.

https://www.exphem.org/article/S0301-472X(08)00388-3/pdf

or this one, i didnt even try to browse it too much, but saw this and that was enough to think there is more in the research that again makes a POINT...NATURAL EPO and rhEPO have different abilities

"Human serum EPO emerged as a broad band after sodium dodecyl sulfate–polyacrylamide gel electrophoresis, with an apparent molecular weight slightly smaller than that of recombinant hEPO (rhEPO)"

http://www.bloodjournal.org/content/98/13/3626?sso-checked=true

but im sure this is all pointless cause its not what rekrunner thinks renato thinks

Would be fantastic if we cotinue to get a steady stream of Kenyan.doping busts and scandals, then to top it all, it emerges that Aouita was the first distance runner to use EPO. Probably 84, maybe even 83.His Belgian doctor was arrested for supplying EPO to dozens of cyclists and runners in the 89s/90s.

that might be nice, but as all the experts on here told me over and over and over and over, no matter what papers i found stating the 1983 date and being mass produced..."no no no minddouche EPO wasnt created till 1988!!!!, now go f*cking kill yourself!!!!" or something like that, it was pretty violent for sure

and then i had to show them that it was the FDA approval was in 1987...but it was being mass produced waaaaay before that for clinical studies...and we all know it doesnt require the FDA for athletes to be on some new sauce...nope 99.99% of the time athletes are waaay ahead of the curve on finding the newest sauce that will give a performance enhancement.

just another one....so much on the interwebs when you do more that just search for "EPO"

now im typing in "molecular differences between EPO and rhEPO"

"Sequential deglycosylation by exoglycosidase treatment (Reagent Array Analysis Method, RAAM) and subsequent sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) revealed a profound structural difference between human endogenous and recombinant erythropoietins"

see that you deniers and renato disciple?

PROFOUND structural differences.....now if natural EPO does what it does, and does a UNNATURAL EPO do with its PROFOUND structural differences do?

yeah im sure renato is right about NATURAL EPO, that you would get from old school blood doping....but rhEPO isnt NATURAL, and is PROFOUNDLY different in MOLECULAR structure. but good thing rek is a Ph D in organic molecular chemistry and is able to explain for us what renato is really thinking

ooops sorry forgot the link

https://www.ncbi.nlm.nih.gov/pubmed/22140023

and here is some more, interesting things out there to read up on

"There are recombinant ESAs with prolonged survival in circulation (‘biobetter’). First darbepoetin alfa (Aranesp®; Amgen) has come, a hyperglycosylated analog (37.1 kDa) of rhEpo, which contains two additional N-glycans in association with an exchange of five amino acids [7]. Compared with the terminal half-life of IV administered epoetin (6–9 h), the half-life of darbepoetin alfa is three- to fourfold longer (25 h), which allows for less frequent application [39]. Another bio-better is methoxy polyethylene glycol-epoetin beta (methoxy PEG-epoetin beta; Mircera®, F. Hoffmann-LaRoche). The half-life of methoxy PEG-epoetin beta (60 kDa) amounts to 130–140 h on IV injection. The prolonged in vivo survival of darbepoetin alfa and methoxy PEG-epoetin beta is in part due to a reduced EpoR binding affinity. 1 μg of darbepoetin alfa or of methoxy PEG-epoetin beta peptide corresponds biophysically to 200 IU rhEpo peptide. Clinically, however, the long-acting products may allow for dose reductions below the predicted 1: 200 ratio"

so basic run of the mill EPO has a 6-9 hr glow

more advanced is 25hrs, and that bad*ss CERA has a 130-140hrs, thats almost 6 DAYS...so what have we learned boys and girls?

well run of the mill EPO is almost IMPOSSIBLE to piss dirty on. and kiprop was warned "a few days in advance" says he must have been on something like CERA for that long of a glow time.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822280/

now pay attention to this

"analogous erythropoiesis-stimulating agents (ESAs)"

behave like rhEPO, as CERA is one of the many ESA's, and look at this from the end of the paper i just posted

"Another strategy has been to replace recombinant ESAs by Epo mimetic peptides (EMPs), synthetic cyclic peptides of about 20 amino acids. EMPs show no sequence homology to Epo but signal through the EpoR (fig. ​(fig.2).2). As the first EMP, peginesatide (Omontys®; Affymax/Takeda) was approved in the USA in 2012 for SC or IV treatment of CKD patients on dialysis. However, the drug was recalled early in 2013, since 0.2% of patients experienced serious and 0.02% of patients experienced fatal hypersensitivity reactions. In an alternative approach, EMPs have been constructed onto human IgG-based scaffolds by recombinant DNA technology. The seminal compound, CNTO 528 (Centocor), increased Hb concentration on IV administration in a phase I clinical trial. The follow-on product CNTO 530, a dimeric EMP fused to a human IgG4 Fc scaffold, was shown to expand the pool of erythrocytic progenitors in vitro and in vivo. However, doubt may be raised as to the advantages of this type of biopharmaceutical over the established ESAs."

so since 2012, there are now EMP's and also ORAL ESA's...but no worries its all myth and placebo on what it can do for athletes.