NOP follower wrote:
I made this thread regarding Salazar's training philosophy, you can take it or leave it.
And part of Salazar's training philosophy includes TUEs, thyroid meds, suspect medicos, labs, equipment aids, etc, etc, it's what NOP is all about, you can take it or leave it.
Suggest you Google philosophy.
You forgot to mention asthma medications:
Beta agonist rage – the anabolic properties of asthma drugs
By Jerry Brainum
Clenbuterol has acquired a near-legendary status among some power athletes. This reputation is is based on the drug's alleged anabolic and fat-burning properties. Although never approved for sale in the United States, clenbuterol is available in other countries under various trade names, including Clenasma, Monores, Norvegan. Prontovent and Spirovent. The drug is sold either in tablet form or as a solution in various concentrations.
Clenbuterol is often mistakenly identified in the popular media as a "steroid". In fact, it is classified as a beta-2 agonist because of its interactions with adrenergic cell receptors, especially beta-2 adrenergic receptors. Since these receptors are involved in bronchodilatation (expansion of the bronchial air passages), the drug is prescribed to help control asthmatic symptoms.
Clenbuterol and similar beta-2 agonists, such as cimatero) and fenoterol, differ from other common beta-2 agonist drugs in that they remain active in the body longer. For example, clenbuterol has a half-life of 27 hours, taking about five days to dear from the body. In contrast the longest-acting beta-2 agonist sold in the United States, salmeterol lasts only about 12 hours.
However, most researchers believe that the longer a drug takes to clear from the body, the higher the risk of side effects. This explains why beta-2 agonists such as clenbuterol have never been approved for sale in the United States. In addition, from the standpoint of asthmatic therapy, the longer-acting beta-2 agonists show no significant therapeutic benefit over existing asthma drugs, so the profit motive for drug companies is also lacking.
CRITTERS ON CLENBUTEROL
Long-acting beta-2 agonists are attractive to athletes for the drugs' putative muscle-building and fat-burning effects. Animal research using various species (e.g., horses, sheep,chickens and cattle) demonstrates that clenbuterol acts as a "repartitioning agent" That is clenbuterol seems to increase the density of type-II muscle fibers (the type most prone to growth in humans) and concomitantly favors bodyfat losses. One study found a 20% gain in muscle coupled with a 20% loss of fat when clenbuterol was given for just eight to 14 days.
Extrapolated to humans, the doses provided in animal research far exceed what any human could safely tolerate. For instance, the average dose range of clenbuterol needed to provide an effective repartitioning response in animals was between 0.33 and two milligrams per kilogram (a kilogram equals 2.2 pounds). The suggested therapeutic dosage to treat asthmatic symptoms in humans is much less. Doses equivalent to those given to the research animals would most likely kill a human.
THE MYSTERY OF CLENBUTEROL
It's uncertain how clenbuterol and similar long-acting beta-2 agonists work to provide anabolic effects. Animals experience a rapid upgrade in muscle-protein synthesis that lasts for only about five days. After that protein synthesis induced by the drug diminishes: then comes decreased muscle-protein degradation, an anticatabolic effect.
A similar scenario occurs with anabolic steroids — an initial increase in muscle-protein synthesis, followed by an extended anticatabolic effect. Both the protein-synthesizing actions and anticatabolic effects of anabolic steroids are known, but how clenbuterol exerts similar activity (in mega-doses) isn't as clearly established.
No formal clinical studies using clenbuterol as an ergogenic agent in humans exist, probably because of the relatively gargantuan dosages needed to produce anabolic effects in test animals. From an anecdotal point of view, most athletes who've taken the drug use it more for its "thermogenic" or fat-burning properties than for its anabolic effects.
However, the beta-cell receptors that clenbuterol interacts with are exquisitely sensitive and are known to "down-regulate" or close up if exposed to concentrated doses of beta-agonist drugs. Athletes often attempt to circumvent this biological limitation by using a "two-days-on, two-days-off" dosing schedule. Even so, the drug usually stops exerting thermogenic effects in as little as two weeks.
NOW, YOU'RE MAKING ME MAD
Clenbuterol is similar in structure to epinephrine, and like epinephrine, clenbuterol can excessively stimulate the heart, resulting in a rapid heartbeat, or tachycardia. Other possible side effects include muscle tremors, heart-rhythm disturbances, headaches and muscle cramps. The latter problem is thought to occur because beta-2 agonist drugs affect potassium distribution in the body.
A few recent inquiries point to a possible behavioral side effect from using beta-2 agonist drugs. An increase in hostility and anger has been observed in men after a down-regulation of beta-adrenergic cell receptors. One study, published in Psychosomatic Medicine (59:481-87, 1997), found that men with decreased cellular adrenergic receptors also showed greater plasma catecholamine (epinephrine) and cortisol responses to anger provocation.
What's curious about this research is that a similar situation - the infamous 'roid rage is reported to occur in some anabolic-steroid abusers. What happens to an athlete taking clenbuterol and anabolic steroids concurrently is still unknown. Could the anger/rage effect be cumulative? And could the danger be compounded further, since investigations have linked increased anger to a higher risk of cardiovascular disease?
The research on clenbuterol isn't completely negative. A study published in Brain Research (717:44-54,1996) found that giving clenbuterol to rats and mice increased a protective brain substance called "nerve growth factor." This effect was especially evident in the hippocampus, a brain area vital to memory storage and intellectual functioning. If this work is reproducible in humans, it may prove that drugs such as clenbuterol might prevent certain types of degenerative brain diseases.
ARE ASTHMA INHALERS ANABOLIC?
Many athletes familiar with clenbuterol might wonder if using commonly available metered-dose asthma-drug inhalers would produce similar responses. It's not unreasonable to assume that such drugs would offer some ergogenic benefits, since they fall into the same beta-2 agonist category as clenbuterol.
The first thing to consider about asthma inhalers is their highly selective distribution. In essence, most of the drug is delivered to the lungs, with some slight spillover into the general blood circulation. Also, the dosage used in such sprays is usually in micrograms — not enough to promote any type of true ergogenic activity.
Despite these notable shortcomings, however, some investigations have confirmed an increase in power in non-asthmatics given asthma inhalers. For example, a 1988 study (Canadian Jouma; or Sports Science. 13:144-48) found that subjects showed improved prolonged exercise performance (lasting more than an hour) after inhaling a commonly available asthma spray drug called albuterol. Most other research has failed to confirm this effect, although a 1992 investigation did find increased power output with the same drug.
A recent report in the journal Medicine and Science in Sports and Exercise (29:1631-36.1997) looked at the effects of another asthma drug inhaler, terbutaline, on 20 elite male athletes from various sports. The drug was used during tow-temperature conditions, which often provoke exercise-induced asthma. The study, however, found no increase in exercise performance in any of the athletes who used the inhaler.
In another case, reported in the Journal of Allergy and Clinical Immunology (99:443-49,1997), a newer type of commonly available asthma inhaler called salmeterol was examined for its ability to increase power output in athletes. Salmeterol is sold commercially as Serevent inhaler and differs from other asthma inhalers because of its extended activity. It binds to beta-cell receptors with an affinity 50 times greater than that of the other most popular asthma inhaler, albuterol. As a result, it lasts twice as long as albuterol (12 hours versus six) in providing increased bronchodilatation.
Any type of beta-2 agonist drug is capable of raising muscle strength by stimulating an influx of calcium into a portion of the muscle called the sarcoplasm. This in turn, leads to an increase in the binding of muscle contractile proteins (actin and myosin), resulting in more potent muscular contraction.
Actually, this process does not usually occur. Regular exercise leads to a release of catecholamines such as epinephrine, which interact with muscle beta-adrenergic receptors. This constant exposure to epinephrine leads to a down-regulation of the muscle receptors (as occurs when drugs such as clenbuterol are used). The result is lowered muscle responsiveness to beta-2 type drugs, such as various asthma inhalers.
The study on salmeterol confirmed the lack of ergogenic or power increases in athletes inhaling this drug in standard doses (two puffs or inhalations). Based on this finding and others discussed above, most asthma inhalers are deemed legal for use in international athletic competition. In contrast, similar drugs, such as clenbuterol are banned.
The main problem with asthma drugs is the same as that typically occurring with clenbuterol — cell-receptor downgrade. Some doctors fear that with continual usage, some asthma inhalers may not work at all thus endangering asthmatics who depend on them. Salmeterol, unlike albuterol, isn't for emergency use anyway; it takes 20-180 minutes to begin opening up the lungs, while albuterol works immediately.
newname wrote:
Love Skinny Legs wrote:Also, think about what you wrote:
"He usually throws in 10-15 200s at the end of workouts ~400 pace, with 200 jog rest"
Flotrack has a workout in which he does 6x1600m in 4:30, and then switches into spikes and does 10x200m in 27-28, ends with 26. So thats the workout addition in practice.
That's interesting, but not what the OP wrote. HE said "He usually throws in 10-15 200s at the end of workouts ~400 pace, with 200 jog rest"
In this video did they jog a 200 and run 20 additional laps after the workout? Also, 28 is not his 400 pace, it is close to mile pace.
OP said 6 X 1600 at 10k pace also, 4:30 is 28:07 pace, or 10 mile pace.
I have no doubt that they do workouts "sort of" like what was listed, I did them myself, but not at the paces listed. Also, note that the OP says "He usually throws in 10-15 200s at the end of workouts ~400 pace, with 200 jog rest."
What is meant by usually? In my world it means it happens most of the time. Even if he meant once per week, I would not believe it.
I believe this one was done at altitude as well. Albuquerque if I recall correctly. Might be more like a 4:20-4:25 effort at sea level.
Alright, so if thyroid medication has been the reason why Salazar's athletes are able to run hard on most days, how do you explain Mary Cain doing similar training? Maybe you guys should try out Salazar's plan before you mock it
"1) It’s a stimulant and that somehow helps performance (how?)
2) “anorexic effects” (Behind the scenes, I’ve heard rumors an athlete might stockpile their prescription and then take extra doses before competition to help lose weight which would presumably help performance)
What are other possible benefits?
It doesn’t take much Internet searching to find people claiming:
4) The thyroid hormone might be able to boost EPO production somehow.
5) It can help recovery and VO2 max.
6) People doping on HGH will have their hormones out of wack, so they need to get on thyroid medication to try and stabilize things" (Weldon Johnson, 2013).
its saying the file does not exist but i would really like to see this
Works for me. Google the title of the article if it does not work for you.
It was interesting to hear the insider perspective of athletes hording their hormone meds to use more of them before competition.
I already have an endocrinology textbook.
NOP follower wrote:
I was thinking of looking through a number of sources to find out what Alberto Salazar's training philosophy is, and then put it all on a single document. Would anyone be interested in seeing it, or would it be a waste of time?
Can someone please upload this again? I didn't get a chance to see it
Hypothyroidism, The Wall Street Journal, Jos Hermens, Mo Farah, Galen Rupp and the Olympics
Share
inShare
by: Weldon Johnson, LetsRun.com
April 10, 2013
The Wall Street Journal today has a full backpage article titled “US Track’s Unconvential Physician” on Dr. Jeffrey Brown who has diagnosed many track and field athletes, including Galen Rupp, Ryan Hall and Carl Lewis with hypothyroidism.
The article indicated Dr. Brown is unconventional because “several endocrinology leaders have never heard of hypothyroidism striking young athletes.”*
The articles delicately discusses the issue noting that the hypothyroid athletes are usually prescribed levothyroxine. The article says “that drug is not a banned substance by the World Anti-Doping Agency and by all accounts has never been shown to enhance performance. Taking it required no disclosure, and no permission from anti-doping authorities.”
Then the article says, “But in the wake of doping scandals all across the sporting world, athletic websites are rife with speculation about hypothyroid medication being used as a performance-enhancing drug. After all proving that a drug improves performance is often difficult.”
Is hyperthyroidism going un-diagnosed for thousands of Americans, or does something about demanding training make it common in elite track and field circles, or is it a secret, legal PED?
Is hyperthyroidism going un-diagnosed for thousands of Americans, or does something about demanding training make it common in elite track and field circles, or is it a legal PED?
Now usually when you see the word “athletic websites” that means letsrun.com. And there have been quite a few threads on hypothroidism and whether its diagnosis is legitimate or abused for performance enhancing benefits.
There are two broad reasons athletes might get on thyroid medication.
1) Their thyroid levels are legitimately out of whack and they want to run and feel better. Just because a bunch of endocrinologists haven’t heard of elite athletes being hypothyroid, doesn’t mean it doesn’t happen. Elite sports science and general population science are very different things.
2) The thyroid drug has other performance enhancing benefits even with a normal thyroid level, so the athletes get a prescription for it when they don’t really need it.
I wish the article had discussed what the possible performance enhancing benefits are, and why athletes might want to abuse this drug. The article hints at two performance enhancing possibilities:
1) It’s a stimulant and that somehow helps performance (how?)
2) “anorexic effects” (Behind the scenes, I’ve heard rumors an athlete might stockpile their prescription and then take extra doses before competition to help lose weight which would presumably help performance)
What are other possible benefits?
It doesn’t take much Internet searching to find people claiming:
4) The thyroid hormone might be able to boost EPO production somehow.
5) It can help recovery and VO2 max.
6) People doping on HGH will have their hormones out of wack, so they need to get on thyroid medication to try and stabilize things.
If you’re more scientifically inclined than me, and have any insight on why athletes might want to abuse thyroid medication, let me know (you can remain anonymous).
Jos Hermens Speaks Out on Thyroid, Is It Harmful?
One thing the article does not discuss, is it harmful for an athlete to take thyroid medication if they do not need it?
That brings me to comments made at the Olympics last year that did not receive much attention outside of the Dutch press.
Galen and Mo Went 1-2 and the Dutch Started Talking About Thyroid
After the 10,000m where the Alberto Salazar coached Mo Farah and Galen Rupp got gold and silver, there were rumblings from some in the Dutch camp (Kenenisa Bekele’s agent Jos Hermens is Dutch) that Mo Farah and Galen Rupp were using thyroid medication for performance enhancing reasons.
All the quotes below were from Dutch journalist Marco Knippen who translated them and emailed them to me after the Games. Many of them were in Dutch or Belgian articles during the Games (here, here, here).
Jos Hermens said, “Science has triumphed over nature. Formally Farah and Rupp are doing nothing illegal. I rather just questioning if Farah during a doping control hands a laundry list of products specified, for which he apparently has a certificate. Within the environment knows almost everyone that it is used. Thyroid hormone affects all. I do not understand why it is not on the banned list.”
Herman Ram the Director of the Dutch Doping authority said, “We know the agent from bodybuilding. Thyroid is very harmful and dangerous to health. There is no discussion. “
Knippen indicated that Ram tried to get thyroid medication on the banned list in 2010 but was unsuccessful.
Pieter Langerhorst, agent and husband of pro runner Lornah Kiplagat, said, “Athletes who use thyroid put their health at risk, even put their lives in jeopardy. This is Russian roulette. The exact risks are indeed not exposed, but I spoke to doctors who said that if you stop using the stuff everything runs away. Therefore it is very frightening.”
All of this begs the question, is thyroid medication dangerous if abused?
And then there is the question of who actually takes the substance. Athletes do not have to publicly disclose their Therapeutic Use Exemptions.
I’ve have never seen conclusive evidence that Mo Farah even takes the stuff. At the Olympics the Dutch journalists did ask Galen Rupp about his TUEs and he replied according to Knippen, “About my personal medical record I do not talk.”
A lot more needs to be known about hypothyroidism and runners. I guarantee Dr. Jeffrey Brown’s phone is ringing off the hook today.
*Read the WSJ article here
More: MB Discussion: Wall St Journal looks at Houston Doc who treats Rupp, other thyroid users
Comments or insight? Email Weldon.
Salazar's philosophy on coaching clearly does not consider ethics, the long-term health of his athletes, or the reputations/public perceptions of his athletes. He was the same way with himself when he was an athlete.
Hey I really liked the outline but why doesn't the link to it work anymore? Does anyone have it saved?
I'd like to see it too
1). Be totally evil.
2). Use as much dope as you can get away with.
3). Cheat now. Don't worry about your future health.
no, nobody cares about this horseshit
OP please repost your outline. At least post it on this thread
Yes. I enjoy reading that type of stuff.
(that doesn't mean I don't march to the beat of my own drummer)
I feel so bad for the OP who is clearly like dead or something