Few here seem to ever consider a middle ground. It's either "let 'em all die!" or "let's tank the whole capitalist system!". The threat remains but, the system will have to adapt to the new reality. There will be winners and losers like there are in any big change.
We will have to wear masks when out and about and gatherings will need to be smaller. Consumerism will need to be curtailed - no more mindless ambling in large crowded shopping malls and fewer stores will exist. More things will be purchased online for home delivery. We will cook more and eat out far less. Restaurant dining will become an expensive "event" reserved for special occasions not something you do out of laziness or a lack of food in your pantry. Take out and delivery will continue for the masses but, the cost will go up.
More office work will be done remotely. This will gut commercial real estate, mass transit, auto sales, and gasoline consumption. On the plus side, the air will get cleaner and many office parks and towers will be converted into housing adding more affordable supply in overpriced markets. People will also become healthier with the reduction in commuting stress and the time lost to sitting in traffic breathing noxious fumes.
Economies will be come more locally based. With many department stores and national chains failing, the opportunity for local entrepreneurs will be enhanced. People will still want to shop at stores for something unique that can't be ordered from Walmart, Costco, or Amazon. This is an opportunity for boutique retailers, mom and pops, and young innovators to enter the market with original products and services.
International travel will again become the province of the monied classes. Flights will get expensive and countries will start requiring visas to enter. Overall, this will help to minimize the spread of pathogens internationally while keeping cultural and environmental treasures from being overrun by mindless tourists more interested in Instagram likes than learning and cultural exchange.
Since this is a running board, I speculate that races will have to change . There will likely be more knowledge gained over the next year or two to assess the risks to larger gatherings of people. Will there be less road racing events? Yes. RDs will go under and corporate sponsors will be much harder to find. Will the remaining events change? Yes. I think that large marathons will require qualifiers to get in much like Boston always has. This will distill the fields down to fitter athletes with less risk of exposure/deadly consequences. Smaller races will shift dates to warmer weather months with less illness (avoiding the usual flu season) and may utilize wave starts or age-group starts with appropriate time in between to spread fields for greater safety. Things like bubble and color runs will cease to exist. I also think that a return to locally produced, minimalist racing will occur featuring "boring" courses in parks, mall parking lots, and office parks - no gimmicks, shirts, medals the size of dinner plates, bands every mile, etc. Pay $10 and race for personal glory on a certified 5K loop for a time, a ribbon, and bragging rights.
We will not have to live under house arrest for 5-6 years. We will all have to adapt to the new world that we live in.