We're going to be in a long economic depression, though it might not appear like one on the surface. We're already in an economic recession by definition (consecutive quarters GDP decline). A depression is a term that is somewhat subjective and not used by Economists anymore. In fact, during the Great Depression the economy actually grew, slowly. Think of a depression more in terms of standard of living and other subjective qualitites.
* We've already borrowed something like $5 trillion for fund the coronavirus lockdowns. The bill is coming due. It comes out to around $15k per American. It's as if everyone in the U.S. just inherited a credit card maxed out to $15k and has to pay it off. Governments are already in the process of passing the tax increases. In Washington state there is a income tax bill making rounds through the legislature. Double-digit property tax increases already taking effect in my city. The local university already has a budget shortfall of over $50 million. Remember in 2007/08 how controversial it was for the government to borrow $700 billion to fund the bank bailouts and how in the following years there was so much political strife over state government austerity measures, tax increases (comes the TEA Party). We're in for that multiplied many times.
* "Virtual" economy causing a misollaction of resources, mismatch of job skills, that will take years to iron. For example, let's say your career and passion before 2020 was Wedding Planner or Violin Player. The career simply doesn't exist in 2020-2021+ because weddings and symphonies are out of comission. Are you going to really forego 2+ years of income and executing your passion and try to revive it in 2022+? More likely, you'll try to retool your skillset for some WFH job that is already overcrowded with ambitious entrants into the profession. Lots of insourcing/outsourcing and downwards pressure on wages. Lots of white collar employment will turn into "gig" work.
* Luxuries that workers have enjoyed, such as business travel (Everyone knows that business travel is a disguise for an all-expenses-paid vacation), lavish Christmas parties, unlimited bus/subway passes in the city, are going away. It's likely that many employers will slash health insurance benefits because of WFH.
* Big events (e,g. concerts, marathons, football games) will be massively scaled down. Price of permits from the city and rent-a-cops will have skyrocketed to increase tax revenue. Lots of new virus regulations to curb activities such as tailgate parties. Businesses that used to sponsor charity road races and did not have to expend that budget in 2020-2021+ will not be able to find the budget in 2022+.
* International travel will be down for the foreseeable future. Vaccine passport requirements and skyrocketting ticket prices will cut down the customer base significantly. But there's a bigger problem than that. We live in the Instagram culture, where things like travel are done for the sole purpose of getting Likes. 2+ years w/out travelling the world will have already adjusted how people get Likes without posting pictures of them holding up the Leaning Tower of Pisa and whatnot. Incentive to travel will be down because of this.
* Virtual economy has freed up a lot of money to be "invested" but it's largely going into speculative assets like Dojecoin or TSLA.