Aside from increased hemoglobin levels, what does EPO do?
Aside from increased hemoglobin levels, what does EPO do?
That's it
From Steve Magness' scienceofrunning blog:
-Interesting study gave 19 Caucasian runners and 20 Kenyan runners and gave them EPO for 4 weeks. In Caucasians, Hematocrit went from 41.9 to 49.2 with EPO, performance improved from 11:08 to 10:30. Then performance was still at 10:46 after being off the drug for 4 weeks. In Kenyans, Hematocrit went from 46.0 to 49.9, while performance went from 9:20 to 8:55, and was still at 9:02 after 4 weeks off drug. ( Blood Parameters and Running Performance of Kenyan and Caucasian Endurance Trained Males After rHuEpo Administration)
Buffalo Orange wrote:
From Steve Magness' scienceofrunning blog:
-Interesting study gave 19 Caucasian runners and 20 Kenyan runners and gave them EPO for 4 weeks. In Caucasians, Hematocrit went from 41.9 to 49.2 with EPO, performance improved from 11:08 to 10:30. Then performance was still at 10:46 after being off the drug for 4 weeks. In Kenyans, Hematocrit went from 46.0 to 49.9, while performance went from 9:20 to 8:55, and was still at 9:02 after 4 weeks off drug. ( Blood Parameters and Running Performance of Kenyan and Caucasian Endurance Trained Males After rHuEpo Administration)
Nice find!
Nice find. The referenced journal article is here: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0056151
Buffalo Orange wrote:
From Steve Magness' scienceofrunning blog:
-Interesting study gave 19 Caucasian runners and 20 Kenyan runners and gave them EPO for 4 weeks. In Caucasians, Hematocrit went from 41.9 to 49.2 with EPO, [3000m] performance improved from 11:08 to 10:30.
In Kenyans, Hematocrit went from 46.0 to 49.9, while [3000m] performance went from 9:20 to 8:55, and was still at 9:02 after 4 weeks off drug.
In summation, EPO increases performance in hobbyjoggers Not shite.
It promotes the survival of neurons after insults like oxygen debt, restricted blood supply, mechanical trauma, neuroinflammation, and excessive stimulation by neurotransmitters.
Mr. Obvious wrote:
Buffalo Orange wrote:From Steve Magness' scienceofrunning blog:
-Interesting study gave 19 Caucasian runners and 20 Kenyan runners and gave them EPO for 4 weeks. In Caucasians, Hematocrit went from 41.9 to 49.2 with EPO, performance improved from 11:08 to 10:30. Then performance was still at 10:46 after being off the drug for 4 weeks. In Kenyans, Hematocrit went from 46.0 to 49.9, while performance went from 9:20 to 8:55, and was still at 9:02 after 4 weeks off drug. ( Blood Parameters and Running Performance of Kenyan and Caucasian Endurance Trained Males After rHuEpo Administration)
Nice find!
So caucasians on EPO are about 1:10 slower over a 3000m than Kenyans not on EPO?
Given how little the EPO increased hematocrit levels in the Kenyans who run 9:20, doesn't this lend at least some credibility to Canova's claim that it doesn't help (or at most only marginally) elite East Africans?