Best one I heard - from one of my colleagues who defended his PhD back in 1991.
Gets to defense and gets two slides into it. One of the committee members interrupts him abruptly and says, "Can we hurry this up? I have a golf "appointment" I have to get to." He then presses the button on the slide reader and holds it, to scroll through all the slides to the last one and goes "In conclusion..." and concludes - skipping the entire meat of the presentation.
Something like a 3-4 minute defense. The guy is a top quality researcher, he just had a really, really easy defense.