fisky wrote:
I'm 72.
I listened to the O'Keefe Ted Talk. Interesting. It confirms what I learned from Dr. Kenneth Cooper 25 years ago. Health and miles look like a ski jump. A little running dramatically decreases mortality risk., similar to going down a ski jump. Then, somewhere between 12 and 30 miles, mortality begins to ramp up a little with increased mileage. Now, it doesn't increase back to the sedentary level. Instead, it looks like the ramp of a ski jump. Yes, it's more risk than ideal, but you're still way healthier than a sedentary person.
Cooper's premise, IIRC, was that the culprit was chronically high cortisol levels that never dropped due to distance training. At younger ages, the body could recover quickly, but with age, the body couldn't recover and as a result, it stays in a chronically high cortisol level.
My subsequent research indicates that chronic inflammation is also a factor.
I take supplements to reduce cortisol and inflammation (not anti-inflammatory OTC drugs) because there are links between high cortisol and inflammation with many of the diseases of aging... COPD, heart disease, cancer, Alzheimer's disease, Parkinson's disease, diabetes, and more.
I also run less than 20 miles a week, but that's a training decision on what works best for me as a 400/800m M70 runner.