I took the last two weeks off from running. Before that I was running about 70 miles per week. Would you see any problem with going back to 70, or would you recommend progressively increasing the mileage? What negative effects can I expect from taking two whole weeks off?
I would simply reduce intensity to a minimum , while retaining the mileage.
i would go like a week at 45-50 then 70, but if you arent injured the 70 is a small risk but a risk. basically, yes it's ok but there is a more conservative route that wont cost you much in fitness. maybe play some sports or ride your bike around during the lower build up week to save some impact and mental fatigue of jumping right back in.