I wouldn't say I "destroyed" my life over running, but I definitely hurt a few years of it. It consumed 7 years of my life. It hurt my education and my relationship with my family. They've forgiven me now, thankfully. Graduate school has now shown me how much more I can achieve when I don't have to: run for 60+ minutes each day, sleep for 9 hours, and be constantly exhausted.
I'm in my mid 20's, and I don't run anymore. I consider it a "good day" when I can walk without pain. I worry about what my legs will be like when I hit middle age. I talk with my wife about how we should purchase a ranch-style home, because stairs might be difficult when I'm older.
I did this to myself by running. I have 2 surgically repaired joints that will never be the same, and may need additional repair in the future. This was not something I knowingly did. One day I felt fine, and then the next day something was clearly wrong. This happened again a few years later, after I quit running competitively. I didn't stupidly run on injuries, but I did stupidly let myself be consumed by running.
Some of my best memories are of races I've run, or scenic long runs in foreign wilderness, but some of my worst also involve running. I would get sick far more frequently than I do now.
If I could turn back time, I would still run, but I would take a few more easy days. When it's 35F and pouring rain, I would take a day off instead of running 13 miles. I would also remember that cartilage doesn't grow back.