Fiction:
100 Years of Solitude, Gabriel Garcia Marquez
Mr. Mani, A.B. Yehoshua
Beloved, Toni Morrison
Dubliners, James Joyce
Moby Dick, Herman Melville (would never have read this one if I hadn't been forced to, but it's a great book)
Midnight's Children, Salman Rushdie
Non Fiction:
Memory of Fire, Eduardo Galeano
Orientalism, Edward Said
The Prophet Armed/Unarmed/Outcast, Isaac Deutscher
I'm leaving the 10th spot open because it's so hard to narrow the choices down.