Having visited 48 of the states and lived for at least a year as runner in 9 of them, the southeast was the clear leader in worst place to be a runner. Now, I get that the Midwest weather can be brutal and their sidewalks seen mythical, but the Alabama in particular took it to another level.
Instead of just verbal abuse hurled my way as in many states, I had objects thrown (think beer empties). I had several cars menace me by driving an aggressive line in areas with no sidewalk, but the capper was the one that steered over the white line and got it's tires on the dirt shoulder at 45 miles an hour at 3pm in full daylight to make me dodge even farther off the shoulder.
Naturally, I adjusted by switching to running at night whenever possible... Can't hit what you can't see. That worked fine until i got pulled over during an interval workout at 10pm. Tried to ignore the officer, but when the lights went on and I was the only soul in sight, well it was an interesting conversation as I explained how experience has taught me that it was safer not to be seen by these locals when running.
Have only run in Mississippi and Louisiana a half dozen days, so they might be worse but those are the only other contenders with Alabama in my experience.