Partridge wrote:
At high altitude the low air density/low oxygen density is a limiting factor in endurance performances. So changes in barometric pressure can easily influence performance (higher pressure means more oxygen).
At sea level there is more than enough oxygen available. The limiting factor is not oxygen density anymore, but how much of this oxygen your body is able to use. Changes in barometric pressure don't have any influence at sea level then.
Air is 20.98% oxygen no matter where you are on earth (at least on solid ground).
What matters is the pressure. The higher in altitude you do the lower the air density and the pressure. "Ideally" sea level under very specific conditions would have a pressure of 760 torr (mm of hg). In Colorado Springs the air pressure is 20% less (about 610 torr). The summit of Everest is about 253 torr.
The partial pressure of oxygen in the air is 21% of the barometric pressure (please note I am assuming no moisture in the air since that will change things). So at SL the partial pressure of O2 (PO2) is 160 torr, in COS it is 128 and Everest is 53.
Your blood also have a partial pressure of oxygen. "Deoxygenated blood" has a PO2 of around 35 torr (at SL, lower as you increase altitude).
It is the pressure that matters since gases move from an area of greater concentration to lesser concentration. If that difference is small as it is in COS and on Everest compared to SL then less oxygen is pushed into the blood.
Adding in moisture in the air drives down PO2.
The reality is that at SL you are rarely going to get a huge drop in pressure that is going to have a huge impact. At altitude you can get enough of a drop to cause issues like acute mountain sickness. My ex got AMS once in Breckenridge because a low pressure front moved in and dropped the pressure enough that as we rode the chair lift up the mountain she became symptomatic.