I've seen as much as a 35 second difference in pace per mile running a marathon in 45 degree temps vs 80 degrees. I'd say 25 seconds per mile of the slower pace in 80 degree temps were on account of blowing up the last 10K due to the heat. Proper pacing is a bigger challenge in a marathon in warm temps -- because the heat obviously exacerbates the cumulative effects. For me it was coasting home to a sub-3 in 45 degrees vs a final 10K death slog in 80 degrees. 80 degrees is okay for a 5K but hot for a marathon, IMHO. So, yes, I think your
pace per mile would come down fairly significantly. Go inside on a treadmill (where it's presumably cooler than 80 degrees) and try to nail your target pace for 10 miles, varying the incline for 60-90 seconds at least once per mile between flat and 1-1.5%. That simulation should give you some confidence you can hold it in more favorable environmental conditions. Good luck!