I run workouts and races in Nike Ekidens. Last spring I bought three pairs. The first pair has well over 500 miles on them now, and they're going strong. The uppers got some small tears at maybe 250-300 miles that made me worry, but they're just through the outer mesh and don't go through the inner liner. They never got any worse really.
I normally wear through the hard rubber on the outside of the heel of my trainers (left shoe always goes first). Considering how little hard rubber there is on the Ekidens, I'm absolutely amazed with how little wear there is on the soles of these shoes. They look like trainers with less than 100 miles on them.