The following is from a Frank Horwill article posted on the serpentine running club website on training to break 4 in the mile:
(http://www.serpentine.org.uk/pages/advice_frank15.html)
A programme to break the barrier
We are now in a position to compile a programme based on physiological data to break the four-minute barrier for the mile:
Day 1 - (Aerobic, 80% VO2 max). Run half-marathon distance 64secs per mile slower than for one's best mile time. Example: best mile time 4:10, run 5:14 / mile or as near as possible to this.
Day 2 - (Anaerobic, 110% VO2max). 2 x 1 x 400 + 1 x 800 + 1 x 300, at 15 secs per 100m throughout. Take 30 secs rest after 400m, 60secs rest after 800m and a lap walk after 300m before repeating.
Day 3 - (Aerobic, 90% VO2 max). Run 10km 48 secs / mile slower than for one's best mile time. Example: best mile 4:10, run 4:58 / mile.
Day 4 - (Anaerobic, 130% VO2 max). 4 x 400, 4 secs per 400m faster than per 400m for best mile time. Example: best mile 4:08 (62/400), run 400ms in 58 secs, 3 mins rest.
Day 5 - (Aerobic, 95% VO2max). Run 5 x 1K at 8 secs per 400m slower than for best mile time. Example: Best mile 4:04 (61 / 400), run at 69 / 400 = 2:52, with 60 secs rest.
Day 6 - REST.
Day 7 - (Anaerobic). 1 x 350, 1 x 300, 1 x 250, 1 x 200, 1 x 150. All full out, with 400m walk after each. N.B. Race every other seventh day instead of this session.
On Day 5, alternate this session each week with an aerobic 100% VO2 max session of 4 by1,500m, 4 secs per 400m slower than for one's best mile time. Example: best mile time 4:02 (60.5 / 400m), run 64.5 / 400, with 3mins rest after each.
How could Day 1 & 3 even be possible? A half marathon at 5:14 per mile for a 4:10 miler? Most 4:10 guys couldn't do that for 7-8 miles much less 13.6. Day 3 calls for a 10k at 4:58 pace for that same 4:10 miler (which would be a significant PR for all of the 4:10ish guys on our team). Am I missing something about his program? Just seems impossible for most MD guys to me.