From what I read (if she was cheating), they do not believe she was injecting it...she must have been ingesting this. It was stated that this would leave the body in 24 hours.
So, if Shelby slipped herself some nandrolone the day before, received a random drug test call, why not avoid showing up? Can't you receive a whereabout failure once without consequences?
Wouldn't it make more sense to do this than risk a possible positive?
Probably one of my biggest questions and very few people are asking it
How many whereabouts failures are you allowed to have? Two? Maybe she already used her limit.
Does anyone have ANY evidence nandrolone is effective orally? Orally-active steroids need specific chemical properties that nandrolone doesn't have.
chipotlenextime wrote:
From what I read (if she was cheating), they do not believe she was injecting it...she must have been ingesting this. It was stated that this would leave the body in 24 hours.
So, if Shelby slipped herself some nandrolone the day before, received a random drug test call, why not avoid showing up? Can't you receive a whereabout failure once without consequences?
Wouldn't it make more sense to do this than risk a possible positive?
A guess that it was ingested as a residual to another substance she was taking.
Harambe wrote:
Does anyone have ANY evidence nandrolone is effective orally? Orally-active steroids need specific chemical properties that nandrolone doesn't have.
it is well digested in the gasto-intestinal tract but rapidly inactivated by the liver - which is why when you take it orally it is quickly cleared, making it an ideal drug for people who wish to cheat.
Nandrolone☆
B.L. Furman, in Reference Module in Biomedical Sciences, 2017
Human Pharmacokinetics
Nandrolone esters are well absorbed from intramuscular sites with an absorption half-life of about 6–7 days (Wijnand et al., 1985). The chemical nature of the ester influences absorption rate and peak plasma concentrations, higher peak plasma concentrations (∼ 30 nM) being achieved after the phenpropionate compared with the decanoate (∼ 14 nM). Plasma concentrations of nandrolone relate well to biological effects in terms of endocrine parameters (suppression of plasma testosterone and inhibin concentrations; Minto et al., 1997). Nandrolone itself, like testosterone, is well absorbed from the gastro-intestinal tract but rapidly inactivated in the liver. Its main metabolites are 19-norandrosterone and 19-noretiocholanolone (Le et al., 2002).
Hubris. Had probably been cheating for a while with no consequences.
chipotlenextime wrote:
From what I read (if she was cheating), they do not believe she was injecting it...she must have been ingesting this. It was stated that this would leave the body in 24 hours.
So, if Shelby slipped herself some nandrolone the day before, received a random drug test call, why not avoid showing up? Can't you receive a whereabout failure once without consequences?
Wouldn't it make more sense to do this than risk a possible positive?
From another thread:
"Conte said nandrolone is often detected when an athlete is taking another banned substance—likely testosterone—that was manufactured in an illicit laboratory that doesn't adhere to strict quality standards and also makes drugs for bodybuilders, who, of course, aren't subject to drug testing. Because nandrolone can be detected in such low quantities, cross contamination from using the same equipment to manufacture other substances can happen.
For example, Conte said, testosterone is often manufactured using glassware, which needs to be cleaned with nitric and perchloric acids. But illicit labs that manufacture testosterone often don't adhere to such rigid standards. If not, it's quite possible the same equipment was cleaned with less powerful acids, leaving trace amounts of nandrolone on the equipment and, eventually, into the batch of testosterone."
I have read no other explanation of Shelby's bust that is as plausible as this one. Women taking testosterone to get an edge in sports is as effective and alluring as ever. Microdosing is safe as well...unless you get a tainted dose.
The thing about micro-dosing is that you’re supposed to be able to beat any drug test because your limits never get high enough. Why invoke extra suspicion with one your whereabouts failure strikes when you think you’re going to beat the test?
There's a good chance they were micro-dosing and the drive-by exposure to pork whatever in the carne asada burrito pushed her over the limit.
Cognitive dissonance allows them to say they've done nothing wrong, as she's probably been micro-dosing for years without it showing.
well absorbed wrote:
Harambe wrote:
Does anyone have ANY evidence nandrolone is effective orally? Orally-active steroids need specific chemical properties that nandrolone doesn't have.
it is well digested in the gasto-intestinal tract but rapidly inactivated by the liver - which is why when you take it orally it is quickly cleared, making it an ideal drug for people who wish to cheat.
Nandrolone☆
B.L. Furman, in Reference Module in Biomedical Sciences, 2017
Human Pharmacokinetics
Nandrolone esters are well absorbed from intramuscular sites with an absorption half-life of about 6–7 days (Wijnand et al., 1985). The chemical nature of the ester influences absorption rate and peak plasma concentrations, higher peak plasma concentrations (∼ 30 nM) being achieved after the phenpropionate compared with the decanoate (∼ 14 nM). Plasma concentrations of nandrolone relate well to biological effects in terms of endocrine parameters (suppression of plasma testosterone and inhibin concentrations; Minto et al., 1997). Nandrolone itself, like testosterone, is well absorbed from the gastro-intestinal tract but rapidly inactivated in the liver. Its main metabolites are 19-norandrosterone and 19-noretiocholanolone (Le et al., 2002).
So it is absorbed more efficiently when injected? But if you’re trying to hide use, smaller oral ingestion makes sense?
As such it is still beneficial if consumed orally?
chipotlenextime wrote:
From what I read (if she was cheating), they do not believe she was injecting it...she must have been ingesting this. It was stated that this would leave the body in 24 hours.
So, if Shelby slipped herself some nandrolone the day before, received a random drug test call, why not avoid showing up? Can't you receive a whereabout failure once without consequences?
Wouldn't it make more sense to do this than risk a possible positive?
Maybe she takes it at 7am every day and so is good for her 6am to 7am test window, but for some reason she didn't clear it as fast this time. Maybe because she ate too much Mexican food so it slowed down the absorption.
Having whereabouts failures does not look good.
chipotlenextime wrote:
From what I read (if she was cheating), they do not believe she was injecting it...she must have been ingesting this. It was stated that this would leave the body in 24 hours.
So, if Shelby slipped herself some nandrolone the day before, received a random drug test call, why not avoid showing up? Can't you receive a whereabout failure once without consequences?
Wouldn't it make more sense to do this than risk a possible positive?
Why do you assume she took it the day before? Maybe she took it several days before and just mistimed the safe window. She would have dodged the testers if she knew she was glowing but didn't realize she had any left in her system.
Former Houlihan fan wrote:
well absorbed wrote:
it is well digested in the gasto-intestinal tract but rapidly inactivated by the liver - which is why when you take it orally it is quickly cleared, making it an ideal drug for people who wish to cheat.
Nandrolone☆
B.L. Furman, in Reference Module in Biomedical Sciences, 2017
Human Pharmacokinetics
Nandrolone esters are well absorbed from intramuscular sites with an absorption half-life of about 6–7 days (Wijnand et al., 1985). The chemical nature of the ester influences absorption rate and peak plasma concentrations, higher peak plasma concentrations (∼ 30 nM) being achieved after the phenpropionate compared with the decanoate (∼ 14 nM). Plasma concentrations of nandrolone relate well to biological effects in terms of endocrine parameters (suppression of plasma testosterone and inhibin concentrations; Minto et al., 1997). Nandrolone itself, like testosterone, is well absorbed from the gastro-intestinal tract but rapidly inactivated in the liver. Its main metabolites are 19-norandrosterone and 19-noretiocholanolone (Le et al., 2002).
So it is absorbed more efficiently when injected? But if you’re trying to hide use, smaller oral ingestion makes sense?
As such it is still beneficial if consumed orally?
It's not really "more efficient" as much as you can avoid the liver breaking it down through intramuscular injection, so you can have it in your system for a prolonged period of time from a single does and don't need to have a needle every single day. Whereas with the pill your liver breaks it down so you have to repeat the dosage. If you are legally taking the drug it's obviously beneficial to take it by injection for long lasting effects. But if you are cheating and subject to random testing, you really want to be able to clear the drug quickly.
Let's see the results of her past tests where it shows zero nandrolone. Her past tests may be right at the threshold and this was the only time she accidentally popped over it. System working as designed.
Hence her FNC statement of "eating at the Mexican food truck all the time." I would bet she's had nandrolone findings before, just none exceeding the limit. Mexican food is Burrito Truck Club's go to excuse.
As others have speculated, she has likely been micro-dosing and beating tests for some time. She screwed up a dosage and got caught. This is good for the sport. Get these cheaters out of there.
nhlgoalie wrote:
As others have speculated, she has likely been micro-dosing and beating tests for some time. She screwed up a dosage and got caught. This is good for the sport. Get these cheaters out of there.
Maybe... i would also add that you can microdose by injection, a low does will not hit levels above the acceptable 2ng/ml, although these numbers are taken from healthy men so a female would likely have needed less than a normal prescribed 50mg dose to stay under.
"A 50 mg intramuscular dose of nandrolone decanoate reaches a mean Cmax 2.14 ng/mL, with a mean Tmax of 30 hours, and a mean AUC of 400 h*ng/mL.1 A 100 mg intramuscular dose of nandrolone decanoate reaches a mean Cmax 4.26 ng/mL, with a mean Tmax of 30 hours, and a mean AUC of 862 h*ng/mL.1 A 150 mg intramuscular dose of nandrolone decanoate reaches a mean Cmax 5.16 ng/mL, with a mean Tmax of 72 hours, and a mean AUC of 1261 h*ng/mL"
How do we know she hasn't already missed one or two other tests, and another missed test counts as a failed one?
chipotlenextime wrote:
From what I read (if she was cheating), they do not believe she was injecting it...she must have been ingesting this. It was stated that this would leave the body in 24 hours.
So, if Shelby slipped herself some nandrolone the day before, received a random drug test call, why not avoid showing up? Can't you receive a whereabout failure once without consequences?
Wouldn't it make more sense to do this than risk a possible positive?
This is my guess.
We know that she was orally ingesting it so it was obviously part of a supplement she was taking. Now it's impossible that she didn't know there was nanodrolone pro-hormone in this supplement because if that was the case you wouldn't defend yourself with some horsesh$t story about a XXXL burrito full of 11 ounces of meat that you didn't order but ate anyways right? If you really didn't know you would please actual ignorance (and stupidity) and maybe you get 2 years and even less on appeal if the CAS is feeling lenient.
I think she was taking whatever she was with full culpability but obviously had far too much trust that what she was taking wouldn't push her above the legally acceptable limits (aka micro-dosing). Here-in lay her problem(s).
1) Trust that what she was taking, on a batch to batch level, was consistent in its composition.
2) Lack of understanding that each humans body metabolizes things differently. It's most likely she was taking over-the-counter stuff like 19-Nor prohormones (just google it) that are either identified in the body as nandrolone or can actually become nandrolone once in the system. It's very possible that at her size and weight that only a slightly irregular batch of whatever she was on could spike her above the legal limits without her knowing.
All of this sounds so incredibly risky and stupid. But I don't know how to frame this up - not only did she get caught, she then compounded her problems by defending herself with an easily debunked tale? Maybe she is, well, stupid?
Long answer short - she thought she was going to pass this test just like every other. She had no idea that she would have a nandrolone marker way above the acceptable limit. She knew she would be on the spectrum because she knew what she was doing - she just never in her wildest dreams thought she would return that number.
Awful coincidence (if there is such for a cheat) - maybe a supplement that wasn't accurate in its composition, maybe an biological situation in her body that caused the metabolization of her supplement to produce more nandrolone then she thought it would.
Play with fire eventually you will get burned.
How do we know she hasn't missed some wrote:
How do we know she hasn't already missed one or two other tests, and another missed test counts as a failed one?
Because she stated that she had never missed a test. Also submitted to a hair sample test which could have flagged chronic use.