While the argument about whether mankind is a significant cause of climate change (between, on the one hand, BRM and Shut-Up and, on the other hand, Outsidethebox et al) is interesting, I don't think it is primary.
I suspect that both hands agree that climate change is caused both by (x) mankind and (y) other factors: the disagreement being over the relative contributions of (x) and (y) and perhaps the meaning of the word "significant".
The question which I would like answered is: "what are the consequences of climate change for mankind?" (For the vast majority of humans, the consequences could be much much more relevant than the causes.)
Without answering that question, there is almost no point deciding what, if anything to do about it. (A) It might be the case (I simply don't know) that the consequences are, largely, positive, in which case we should sit back and enjoy the change and (in London for example) look forward to Mediterranean cafe culture beginning where it never once was. (B) Alternatively, the consequences might be largely negative. In this scenario mankind might need to act (and of course, this is the case whether the cause of climate change is (x) or (y)).
Assuming (B) (not something I am prepared to assume myself, just for the sake of argument), a cost/benefit analysis should be undertaken concerning any actions. It might be the case that the cost of taking action outweighs the benefits: in which case action should not be taken. I'm using "action" very widely here: action could be, for example, saying that all future emissions of CO2 must stop and we should return to a Medieval existence, or it could mean that we just change our living spaces to cope with the new climate, or it could mean that we decide to move populations from one part of the globe to another.
(Parenthetically, I might add, when considering the cost of an action, one should always consider the opportunity cost. For example, if mankind focuses huge amounts of resources on tackling climate change by reducing C02 emmissions and thereby is poorer has fewer resources focused on reducing the amount of African women who die in childbirth then that might be a huge oppotunity cost.)
A lot of these questions are political rather than scienctific. And therefore while I respect the opinions and advice from scientists (or even the majority of scientists!) I don't consider it in anyway conclusive as to action that should be taken. I do wish there more debate on these things.
I also realise that I've just re-worded an earlier post of mine in this thread without adding much new - apologies.