I'd love to know what his basis for thinking this is. Has he run some flying 200's in training under 22.5? I just don't get why you would say that unless you have absolutely zero clue about your body, it's strengths and weaknesses and the physiology of the sport and it's events (maybe be doesn't).
Look Nuguse is hugely impressive. I picked him to make the Olympic team and he did. But the first time I ever saw him run was the solo 3.34 at the ACC champs (I hadn't even seen the 2019 NCAA win at that point) and I remember thinking "THIS guy won the NCAA and ran 3.34?" and I said that for the sole reason of his running form - very low "bucket" hips and swaying arm carriage. But hey, he is tough as nails both physically and mentally and the 1500m/mile is ultimately an endurance/strength event.
But that's beside the point - Jared can work on his speed all he wants - there is zero chance he will ever, EVER even get close to 46 seconds in an open 400m - not even in a relay. I am just going to chalk this one up as amusing and pretend like his was deliberately making fun of himself which he very well might have been.