Explain why it is recommended to wait 1-2 hours after waking up to ingest caffeine?

Thanks for the link. I will give it a listen. My hypothesis is that he might be right in terms of the effect on adenosine. The question would be: is it physiologically relevant? Does it really make one bit of difference?

Makes me think of the overnight fasting stuff and yes it did some things and it turned out they are not that meaningful.

LetsRun gaffes .....coffee dehydrates you, lactic acid, VanCortland Park, Journey, .....

I believe the answer relates to cortisol levels. Cortisol is much stronger than caffeine at the "waking" effects. If you pair high levels of cortisol secretion with caffeine, all you're doing is increasing your tolerance with little additional effect. The optimal approach would be to pair your coffee with decreasing cortisol levels.

I've never heard this advice, and therefore I've never abided by it.

I'm 32 years old and I've not died yet.

Last ultra I trained for, aged nearly 60, in training I would wake up, have a cup of coffee, glass of water, maybe another coffee (gets the bowels going), have a good crap and maybe another water and out the door , unoptimised, within about 30min of waking.

30km, no electrolyte, just water from taps along way, around 4:40 (per km) pace, finishing strongly. I did the ultra passing through the marathon in 3:15, all with unoptimised physical performance. Only had electrolyte/water in race

...and btw, all instant coffee, as I am not a regular coffee drinker, just the 'first thing in morning one' to get the crap out of the system

You may not have died yet, but have you lived yet?

Science shows. To feel alive, you must optimize.

It is not me that butter is killing...

Sounds nonsensical. I typically wake up to pee about an hour before I want to actually get up, swallow a 200mg caffeine capsule with a bit of water, go back to sleep, wake up about 60 minutes later; have about two cups of iced coffee (probably about another 200 mgs of caffeine, and go about my day.

Academics are a waste and constantly need to justify their existence with this nonsense.

Once you get tenure at Stanford any opinion you have is science. I thought you guys knew this.

Dear diary,

This morning I received a coffee Enama 14 minutes after waking. They say that it is normal to be emotional during the experience and sometimes cry. Friends, I wept tears of pain, hatred, and joy for 73 minutes straight. Now I fear that the caffeine is beginning to wear off and I am starting to crash. Emoji sad face.

Huberman does indicate it makes sense to drink coffee right away if you plan on exercising right away:

"Caffeine merely blocks the adenosine receptor, but doesn’t clear adenosine. Allow the first hour or two of your day to clear adenosine with light and movement. Then drink caffeine. An exception is if you exercise right after you get up. In that case drink caffeine on waking."