I wore several different sorts of orthotics for years, with success. But at a certain point as I aged, as the possessor of hallux rigidus in my left big toe, I found that I did better with just thin, flexible carbon plates and no orthotics.
A key element of my development was realizing, after reading BORN TO RUN, that I did better, and felt much better, with very little heel offset (lift). For years I wore Brooks Adrenaline plus orthotics; the combined offset was probably 15 mm. That's insane--although I didn't realize it then.
Three or four years ago, I visited the Boston running store right in that final straightaway of the marathon, and a young saleswoman listened to me talk about how I just felt better, with a more natural stride, in racing flats. She put me in Saucony Kinvara with 4 mm. of offset. Night and day! Thinking back, it's as though I'd been laboring with unnecessary offset all those years.
Getting rid of the orthotics was part of that trimming-back dynamic. I do just fine with no orthotics, just those carbon plates, which I slip under the skinny shoe pad--whatever that removable insert is that all shoes have. My biomechanics are good, despite my hallux rigidus. No knee problems, no hip problems. My stride feels great. Powerful. I train AND race in the Kinvaras. I'm no minimalist, but I'm definitely trending in that direction. Less is more.
I can't speak for everybody, but if I were you, I'd first try my cure: thin flexible carbon plates (thin is key), no orthotics, low offset.