old guy II wrote:
Charlie, here's a new study consider in dealing with the aging process,
https://www.nature.com/articles/s41591-019-0673-2
I had a quick look through this (thank you scihub). There is no quick and easy take home message. In fact it's pretty heavy going if you are not familiar with modern genomics techniques. Interesting that the proteins that mark for aging come in three waves, peaking around 37, 60 and 80 years old (4,000 people, so no small sample problem).
Here are the last few "they would say that wouldn't they" sentences:
"Specifically, identifying plasma proteins that promote or antagonize aging at different stages of life could lead to more targeted therapeutics and/or preventative therapies. Such reliable tests and treatments are urgently needed for several diseases, and, in the future, we hope to describe plasma proteome changes that predict subjects transitioning to disease. Of particular interest are studies of Alzheimer's Disease, for which blood-based biomarkers are unavailable, and clinical symptoms are believed to occur up to two decades after disease onset."