There are several studies that show a decline in VO2max (and one can assume that extends to performance) at mild altitudes as low as 600m.
See papers by
Gore et al - JAP - decline in VO2max at 600m
Chapman et al - MSSE - decline in VO2max at 900m, predicted by SaO2 at VO2max at sea level
Terrados et al -- decline in VO2max at 1000m
The old school thinking was that altitude didn't affect VO2max until 4000ft (Buskirk et al). We know now that in highly trained distance runners, especially ones who exhibit exercise induced hypoxemia, that VO2max (and performace) declines essentially start as one ascends up from sea level. This is because SaO2 is already on the steeper downslope of the oxyhemoglobin dissociation curve during max exercise at sea level in EIH athletes. Any change in PO2 can not be "absorbed" by the flatter top slope of the Hb-O2 dissociation curve in these athletes. The EIH probably comes from a transit time limitation of RBCs in the lung......
Lesson over for today.
Fizz-e-ologist