EPO and the placebo effect

"Thermoregulation

The transport functions of the blood during exercise

are not only that of supplying active muscle with fuel

and oxygen and carrying away the metabolic products

of muscular activity, but also to transport heat away

from the exercising muscle and to enable it to be dissipated without the core temperature of the athlete rising to dangerous levels. In many forms of endurance

exercise, particularly in hot conditions, a significant

part of the cardiac output is involved in heat dissipation with blood being shunted through the superficial

layers of the skin to dissipate this heat. This part of the

cardiac output is therefore not available for the transport of oxygen to the exercising muscle; thus, performance is limited. If, because of a raised haematocrit

from blood doping, a smaller proportion of the total

cardiac output can supply the same amount of oxygen

to exercising muscle, this releases a larger component

of the output for this secondary role of heat dissipation

which can therefore be more efficient and will allow a

higher work rate in unfavourable environmental conditions. Studies by Sawka et al. on exercise in a hot

environment suggest that infusion of 900 ml of autologous freeze-preserved blood confers considerable

advantages in terms of thermoregulation during endurance exercise"

Oh my oh my

Thermo dino wrote:

his paper reviews the influence of several perturbations physical exercise, heat stress, terrestrial altitude, microgravity, and traumasickness on adaptations of blood volume BV, erythrocyte volume EV, and plasma volume PV. Exercise training can induce BV expansion PV expansion usually occurs immediately, but EV expansion takes weeks. EV and PV expansion contribute to aerobic power improvements associated with exercise training. Repeated heat exposure induces PV expansion but does not alter EV. PV expansion does not improve thermoregulation, but EV expansion improves thermoregulation during exercise in the heat.

Oh my.

Yes, and I have been writing about this here for....how many years?

The first half of that is correct. The second half is in direct contradiction of thermoregulation.

For the obvious reason that sweating uses lots of energy.

I wrote to Pitsiladis in 2014 expressing my concerns that he should be aware of this.

If you read Andrew Jones' most recent paper you will see that he does not subscribe to the superhuman oxygen uptake hypothesis.

Did he laugh really hard?

Nobody said superhuman, they just mean better than you can do clean.

Raising a 60 to a 65 is not superhuman.

Superhuman would be having the max of a racehorse. Do they defy physics and thermoregulation with their max of over 150?

citric acid cyclist wrote:

Thermo dino wrote:

his paper reviews the influence of several perturbations physical exercise, heat stress, terrestrial altitude, microgravity, and traumasickness on adaptations of blood volume BV, erythrocyte volume EV, and plasma volume PV. Exercise training can induce BV expansion PV expansion usually occurs immediately, but EV expansion takes weeks. EV and PV expansion contribute to aerobic power improvements associated with exercise training. Repeated heat exposure induces PV expansion but does not alter EV. PV expansion does not improve thermoregulation, but EV expansion improves thermoregulation during exercise in the heat.

Oh my.

Yes, and I have been writing about this here for....how many years?

That blood doping works? That was the point of that.

You are also confused as to how increasing capillarization increases the volume over time. Nobody has disputed that volume increases quickly. They disagree that it maxes out in a few weeks.

Thermo dino wrote:

citric acid cyclist wrote:

Yes, and I have been writing about this here for....how many years?

That blood doping works? That was the point of that.

You are also confused as to how increasing capillarization increases the volume over time. Nobody has disputed that volume increases quickly. They disagree that it maxes out in a few weeks.

Huh?

If you put more plumbing in your house you have more water in the pipes.

In layman's terms.

Or in clap your hands over your ears and running to your safe place:

https://link.springer.com/article/10.1007/s00421-016-3419-6#:~:text=Untrained%20subjects%20may%20enjoy%2010,untrained%20individuals%20(Ingjer%201979)

.

Thermo dino wrote:

If you put more plumbing in your house you have more water in the pipes.

In layman's terms.

Capillarisation continues throughout your life.

A 70 year old plodder has more capillaries than a 17 year old sub 4 miler.

Steve Cram ran 3.57 for the mile and 3.40 for 1500 at that age.

No drugs needed to be the first man under 3.30 for 1500, it was a natural progression.

Thermo dino wrote:

And a multiple major winner and gold medalist. Other metrics used to define top athletes. Actually more important since few athletes actually set records. What does Farah have, one?

Yes -- she is also all these things, while significantly slower than top athletes.

Maybe this more important if you want to make other points.

It certainly seems important to you to tell me my focus on best times are less important.

Mo Farah is similarly all-time slow.

rekrunner wrote:

Mo Farah is similarly all-time slow.

But is he a top athlete?

citric acid cyclist wrote:

Thermo dino wrote:

If you put more plumbing in your house you have more water in the pipes.

In layman's terms.

Capillarisation continues throughout your life.

A 70 year old plodder has more capillaries than a 17 year old sub 4 miler.

Steve Cram ran 3.57 for the mile and 3.40 for 1500 at that age.

No drugs needed to be the first man under 3.30 for 1500, it was a natural progression.

Nope. It starts to decline with age.

Irrelevant.

and also the Cram reference is a Red Herring.

Thermo dino wrote:

rekrunner wrote:

Mo Farah is similarly all-time slow.

But is he a top athlete?

Yes, for 1500m.

rekrunner wrote:

Thermo dino wrote:

But is he a top athlete?

Yes, for 1500m.

12th all time over 1500m , WR at the indoor two mile.

Thermo dino wrote:

citric acid cyclist wrote:

Capillarisation continues throughout your life.

A 70 year old plodder has more capillaries than a 17 year old sub 4 miler.

Steve Cram ran 3.57 for the mile and 3.40 for 1500 at that age.

No drugs needed to be the first man under 3.30 for 1500, it was a natural progression.

Nope. It starts to decline with age.

Irrelevant.

Wrong. And address the issue about Cram.

citric acid cyclist wrote:

Thermo dino wrote:

Nope. It starts to decline with age.

Irrelevant.

Wrong. And address the issue about Cram.

Correct and Red Herring,

See?

https://www.fightaging.org/archives/2019/06/declining-microcirculation-as-an-important-aspect-of-aging/#:~:text=Many%20studies%20have%20shown%20that,scale%2C%20resulting%20from%20inappropriate%20cellular