Scientists & doctors please chime in - Is EPO a prescription given to malaria patients as a 2:05 marathoner claims?

Those poor malaria infected people. It was a good thing that Dr. Rosa got there in time to help them.

pop_pop!_v2.2.1 wrote:

3rd world probs wrote:

In simple, yes. As outlined above, destruction of erythrocytes secondary to disease as well as medications to tx the disease both cause anemia. There is currently a movement for utilization of epo for tx of anemia in 3rd world countries secondary to malaria because of the sketchy blood available for transfusion.

Ok, all good. But.....

We're talking about a theoretical malaria-ravaged health condition to RUNNING A MARATHON at national elite times or better, in a matter of a few days.

That's the only possible way to test positive is to test very close to a non-micro dosage window, 2-3 days. Maybe the urine test has gotten better? Add a day or two.

If recovery is that instantaneous, then I'm happy to have my doubts removed. Otherwise, this excuse is fantastic.

Great, now we have them taking EPO for malaria, maldonium for their "magnesium deficiency, heartbeat irregularities and to guard against diabetes", throw in some thyroid medication and who knows what else and you're scratching your head at how they manage to get to the start line, let alone compete.

Clerk wrote:

Sounds feasible. wrote:

Sounds feasible, it also helps prevent tooth decay if you put it in your toothpaste.

Not unlike that nandrolone spiked toothpaste:

http://www.cyclingsupports.com/wp-content/uploads/2016/02/38-8-e1456299595689.jpg

He looks nothing like Dieter Baumann.

Metric Miler wrote:

pop_pop!_v2.2.1 wrote:

Ok, all good. But.....

We're talking about a theoretical malaria-ravaged health condition to RUNNING A MARATHON at national elite times or better, in a matter of a few days.

That's the only possible way to test positive is to test very close to a non-micro dosage window, 2-3 days. Maybe the urine test has gotten better? Add a day or two.

If recovery is that instantaneous, then I'm happy to have my doubts removed. Otherwise, this excuse is fantastic.

A quick Google search has led me to believe that it was an out of competition test. He didn't need to be racing or training to be subject to the test.

Uhhh. So... He's so sick with malaria his blood values are dangerous, but gets up and goes to a test???? Is this some kind of walking malaria?

...after the outbreak of the contagious Kenyan weak mind disease at the training camp of Claudio Berardelli...he had his contract terminated by Frederico Rosa.

http://athleticsillustrated.com/editorial/claudio-berardelli-has-contract-terminated-in-light-of-more-kenyan-doping/

Frederico Rosa...of course has lots of money...

...and then bought his own blood testing machine...to show everyone his Kenyan runners are clean..

...so far it is over one year and 3 months later...and no blood test results from any top tier Kenyans have been made public by manager Frederico Rosa...

rjm33 wrote:

The site

http://www.kenyarunners.com/pages/167372/index.htm

...also states that EPO was available in Europe as early as 1984...which means all of my previous research which established the earliest verified use of EPO by any endurance athletes in any sports as 1986 may be wrong!...since I was basing my information on US availability of EPO..

...EPO may have been available in Europe earlier than the US...I will try to check..

This is very interesting if true...Alberto Cova won 1984 10K gold for Italy, and in 1988 Salvatore Antibo won 10k silver (gold was won by Boutayeb(sp) a Moroccan runner!)...and Gelindo Bordin of Italy won the 1988 marathon gold, and Boston 1990...

.......this story gets better every day!....

I don't think that information is correct. From all the research I've done reading articles on Internet, the first clinical testing began in 1985, its first use for renal therapy started in 1986/87, and the first therapeutic licence for it's medical use was only granted in 1988. I think the first known record of its use in cycling was 1989. I doubt any athlete used it until the 1990s.

fred wrote:

Those poor malaria infected people. It was a good thing that Dr. Rosa got there in time to help them.

Indeed. Otherwise they might have gotten weak mind disease too.

I have 1986 to 1987 as earliest EPO use...as you can see from this article on the DEATHS of 18 young Dutch and Belgian cyclists in the years 1987 to 1990...

http://www.nytimes.com/1991/05/19/us/stamina-building-drug-linked-to-athletes-deaths.html

Renato Canova has also already stated on the "EPO and mid distance thread" that Alberto Cova and Salvatore Antibo did do blood transfusions before they were banned in 1985 (even though there was no test for detection of transfusions).

Renato Canova has also stated that Salvatore Antibo stopped blood transfusions with the 1985 ban because he found that just doing altitude training was more effective than blood transfusions.

Renato Canova has also stated that Gelindo Bordin never did any blood transfusions, or EPO, and only used altitude training.

In 1986, Renato Canova became responsible for the Italian marathon team, along with his good friend Luciano Gigliotti, who was the coach of 1988 Olympic marathon gold medalist Gelindo Bordin and 2004 Olympic marathon gold medalist Sefano Baldini.

https://en.wikipedia.org/wiki/Renato_Canova

EPO can help a person with malaria but only when the RBC have dropped to extremely low levels.

I am sorry, but that had a spelling error...that was Pamela Chepchumba that was EPO positive in the 2003 world cross-country championships.

Emily Chebet came in 5th in the junior women's race back in 2003, that was won by Tirunesh Dibaba.

Emily Chebet later became senior women's world cross-country champion in 2010 and 2013.......however in 2015 Emily tested positive for the diuretic furosemide which is used as a masking agent...and she is now serving a 4 year ban from competition.

MD^10 wrote:

EPO can help a person with malaria but only when the RBC have dropped to extremely low levels.

I am a hematologist, not an infectious disease specialist, but if a patient's hemoglobin has dropped to dangerously low levels (as can occur with severe malaria), it makes absolutely zero sense to administer EPO as opposed to provide said patient with a simple blood transfusion. The transfusion kicks in immediately whereas EPO takes a number of days to fully take effect. This is a BS excuse from a doper (or his agent) and nothing more.

I think Martin Lel said he had malaria before the 2008 Olympic marathon and said it was a miracle to finish 5thThat said, malaria is so prevalent in East Afroca that I am not sure that it is indicative of a doping cover up. Maybe but I would need to see more.

rjm33 wrote:

Oh my!

Here is a partial list of Kenyan runners who have had bouts of malaria:

1) Cosmos Ndeti

2) Moses Kiptanui

3) Paul Tergat

4) Dennis Kimetto

http://www.kenyarunners.com/pages/167372/index.htm

Keep reading the whole site page down!

...the Italian manager Dr. Gabriele Rosa (who was manager to Moses Tanui and Paul Tergat, and many other famous Kenyan runners both male and female) and EPO use rumors by top Kenyan runners is discussed a lot on this site!.....

titaniumbolt wrote:

MD^10 wrote:

EPO can help a person with malaria but only when the RBC have dropped to extremely low levels.

I am a hematologist, not an infectious disease specialist, but if a patient's hemoglobin has dropped to dangerously low levels (as can occur with severe malaria), it makes absolutely zero sense to administer EPO as opposed to provide said patient with a simple blood transfusion. The transfusion kicks in immediately whereas EPO takes a number of days to fully take effect. This is a BS excuse from a doper (or his agent) and nothing more.

You're taking for granted the large supply of safe blood that is available for transfusion in the US. People are still getting HIV and Hepatitis from blood transfusions in Asia. Given this, it's understandable that physicians in that part of the world might seek alternative treatments.

800 WR holder Wilson Kipketer contracted malaria in '98, and returned, but never broke 1:42 again. He did win WCs in '99.

You are right...malaria is prevalent in Africa...so it could just be a coincidence.

But the world record holder in the marathon running 2:03... 6 weeks after a bout of malaria...which causes anemia!...seems almost too unbelievable!...

...this is starting to sound familiar to another thread... which is now becoming very boring...

The Italian connection is key. Look at what Dr. Francesco Conconi was publishing a study about in the year 1988, the same year EPO was banned by the International Ski Federation that governs cross-country skiers:

http://www.ncbi.nlm.nih.gov/pubmed/3384528

https://en.wikipedia.org/wiki/Francesco_Conconi

http://www.iaaf.org/athletes/kenya/martin-kiptoo-lel-191629

For another coincidence...

Martin Lel won the World Half-marathon Championships at Vilamoura in 2003 ...the same year that Paula Radcliffe won the women's championship race. I have heard it was warm that day... but nobody in the world knows what the actual temperature was during the race that day!

For another coincidence, as you can see from the link above...Martin Lel was coached by Claudio Berardelli... and his manager was Frederico Rosa...

Frederico Rosa has also stated in previous interviews... that when his athletes need medical attention, he sends them to an Italian doctor located in Nairobi, Kenya. When asked by the interviewer what the name of the doctor was...he said that he would prefer to not name the doctor that he uses.

In this interview...Frederico Rosa mentions the Italian doctor that he will not name and in the interview he states that both Rita Jeptoo (EPO positive) and Matthew Kisorio (anabolic steroid nandrolone positive) both told him that they had been to doctors to treat their bouts of MALARIA.

...just another coincidence...

http://running.competitor.com/2014/11/news/rita-jeptoos-agent-federico-rosa_117410

The more you read...the more interesting things get...every single day.

Everyone in subtropical Africa gets malaria. It's the deadliest disease in the world, killing 3 million people every year.

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Cerebral malaria: protection by erythropoietin.

Bienvenu AL1, Picot S.

Author information

Abstract

Cerebral malaria (CM) is still responsible for unacceptable death rate, while new antimalarial drugs were recently developed. CM pathophysiology shares essential biological features with cerebral ischemia. Because erythropoietin (Epo) was demonstrated to reduce mortality rate during experimental cerebral ischemia, in the early 2000, we wondered whether Epo could help to reduce the burden of CM. There is now evidence that Epo high doses could prevent early mortality during cerebral malaria. This evidence was obtained first using mice model of cerebral malaria, and later confirmed by prospective clinical trial in endemic area. High doses of Epo are needed to cross the blood-brain barrier and to favor the cytoprotective versus hematopoietic effect of this pleiotropic cytokine.