Sub 16 min guys wrote:
This is interesting, I’m curious how to specifically train your body to increase glucose uptake.
I saw this claim years ago, but since I don't do distance racing, I didn't bother to follow up. Here's the source for the claim, per a perplexity.ai prompt. I haven't read it so I don't know the protocol. Maybe it's described in the paper.
Perplexity.ai wrote:
The source "Training the Gut for Athletes" by Asker E. Jeukendrup published in Sports Medicine (2017), accessible through PMC, states that the absorption capacity for glucose via the sodium-dependent glucose transporter (SGLT1) in the small intestine typically limits exogenous carbohydrate oxidation to about 60 grams per hour. However, when multiple transportable carbohydrates such as a mixture of glucose and fructose are ingested, which use different transport mechanisms, oxidation rates can increase beyond this typical limit. Carbohydrate oxidation rates have been observed to reach higher levels such as approximately 90 grams per hour or even up to 120 grams per hour in some studies, by combining glucose with fructose.[1]
This is achieved because fructose is absorbed via a different intestinal transporter (GLUT5) than glucose (SGLT1), allowing for a higher overall carbohydrate uptake rate than with glucose alone. Training and dietary adaptation can increase the number and activity of these transporters over as little as a few days to weeks, further improving absorption capacity.
In summary, while glucose absorption alone peaks around 60 grams per hour, carbohydrate absorption exceeding 90 to 120 grams per hour is possible when combining different types of sugars and with gut training. This is an important physiological basis behind high carbohydrate fueling strategies in endurance sports.[1]
[1](https://pmc.ncbi.nlm.nih.gov/articles/PMC5371619/)