casual obsever wrote:
griles17 wrote:
Methodical demolition of the doping accusations against Shelby and the approach taken by CAS. Thoughts?
There are several problems with that:
"Fact #1: One of the tests that the laboratory used has a 40% false positive rate!"
False. No false positivity rate whatsoever; no one tested positive for nandrolone who shouldn't have. Fact: 2 of the 5 participants showed high delta-13C values after eating (German or Estonian) wild boar because of their diet. This does not apply here, with the meat being from commercial pigs "with largely corn-based diet" (see CAS report).
"There is no question that once the Houlihan legal team invoked the WADA clause on January 19, 2021 that the nandrolone came from pork consumption, the GC/C/IRMS test should not have been performed on the B sample. Instead, the analysis should have focused on the "pharmacokinetics of 19-NA excretion."
Incorrect, see CAS decision. That was very much a question, and ultimately it was ruled that the lab used the correct procedures.
Plus, the (optional!, note the "may be") pharmacokinetics tests are only meant to differentiate between ingestion and injection, not between e.g. boar and Deca:
Wada: "Therefore, if the consumption of edible parts of intact pigs is invoked by an Athlete as the unlikely origin of a 19-NA finding, this may be established based on the pharmacokinetics of 19-NA excretion [3, 5, 16-18]. Profiles of 19-NA and 19-NE excretion following oral ingestion will have a different time course than following an injection of 19-norsteroids."
"AIU should realize that they are damaging the reputation of anti-doping organizations by ignoring WADA guidance, despite a 2-1 victory at the CAS hearing."
Incorrect, WADA guidance wasn't ignored, see CAS decision. It was ruled that the lab followed WADA guidance.
"This 2008 research showed in Table 2 that ingesting 300 grams (10.6 ounces) of uncastrated pig organ meat could lead to as much as 130ng/mL of 19-NA in the urine: more than 25 times higher than the 5ng/mL."
While correct, this is misleading: the food truck in question serves boar stomach as boar offal, not kidney etc. as in that Table 2.
"In Table 2, there are measurements of 19-NA levels in urine after ingesting uncastrated pig meat (not the organs). You can see that it is not only the organ meat ingestion that can lead to reliatvely high levels of 19-NA measured in the urine and potentially cause a drug test fail."
Misleading at best. "relatively high levels"? They were 0.6 to 2.4 ng/ml after eating 300 g wild boar meat, unlike Houlihan’s 5.2 – 5.8 ng/ml after eating 140 – 180 g commercial pig stomach.
"Fours Reasons That Shelby Houlihan Would Not Dope With Nandrolone"
Misleading at best, like in JG’s piece. For example, they neither considered that it could have been given sublingual instead of oral, or that the athlete chose oral (with less benefits) instead of an injection because that’s harder to detect (see the concept of microdosing for comparison).
Plus, as cited here on letsrun several times, nandrolone occurs as contamination in other steroids, such as in the good old testo cream that the athlete might have used. That option also did not get mentioned, neither by JG nor by Twoggle.
But you don't even know what Deca is. So why are you pretending to be an expert on Nandrolone metabolism?