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Middle Ground
RE: Wired's Nicholas Thompson on Boston: "It’s a terrible course if you want a personal best." Agree or Disagree
The most salient point in the article is that "wily veterans" can do well. Assuming the wind is not a major factor, the key to the course itself is not pummeling your quads on the downhills in the first few miles. The pace feels so easy aerobically, it's easy to get sucked out and hammer the legs. The Runners Connect Boston Marathon Pace Calculator calls for the first two miles to be significantly slower than goal pace, despite being net downhill miles. Tough to do when you are charged up and feeling good.

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