Jesus you're so obtuse I see why people think you're trolling.
0. People that take drugs do NOT know appropriate doses. They do not understand that after lengthy periods of being clean their tolerance levels are significantly lower than they expect. This is how a large majority of overdoses occur. By far and large, the average addict do not know doses in terms of biological "safety." They may know 150ul of LSD is a hard trip and 50ul is a light one, but mix that drug with any other one and you have a recipe for disaster. Glad you ignore EC50, since that is literally the toxicology method of studying the power of a drug. If an alcoholic who is used to 20 drinks in a night quits, and 20 years later starts up again he won't get to 20-- he'll pass out and have a hangover but be fine the next day. A cocaine or opioids addict who does the same will have no biological signal that the drug is too much, they take it all at once (something practically impossible with alcohol) and they die.
1. You really think meth addicts fare better than alcoholics? Meth addicts wither away their brain. Alcohol just numbs you. You do not know what you're talking about.
Sure, alcohol is bad. But you didn't say the drug which causes the most damage to society, you said the most powerful. That is a biological question, probably even a chemical one, not a sociological or off-the-cuff analysis question.
2. You basically contradicted yourself when you said that dosages don't matter since addicts know doses. But then you say some drugs only affect you at high doses. Wouldn't an alcoholic know their dose? When does it matter and when doesn't it? What's a high dose of alcohol? Drink bleach. Half a cup of concentrated bleach will kill you. You can buy bleach OTC without an ID. I'd wager that's a more powerful drug than alcohol by your standards alone.
3/4. Jesus yeah you're trolling. Those side effects are significant for ANY GABA agonist like alcohol. It's way easier to die off of benzo's than alcohol because with benzos you take 6 of them in a day, 2 at a time, because you're forgetful and can't read directions. You drift away to sleep and you're dead. With alcohol? You have to drink 10-20 shots+ depending on your body composition to go into alcohol poisoning. That's considerably harder, and arguably harder to obtain than benzos once you actually have the drugs in your hands.
So because of nomenclature you're claiming alcohol is more powerful? Cool just making sure. Alcohol detox is worse than most other drugs (though they're still horrible) because you typically don't abuse drugs that change the fundamental way your global central nervous system works over abuse in extended periods of time. Opioids affect few receptors and few systems in the brain, most people go there-- same with cocaine and stimulants. Alcohol is worse because we let it get worse. Cocaine addicts and meth addicts happen much sooner based on the mechanism of action of the drug itself, so even by your logic the addictive capacity of these drugs is way worse than alcohol. We treat them, they come in to rehab, or they run out of money, the rest die after years of selling their bodies or stealing everything in sight to buy a new hit. With alcohol, it isn't like that. There are no "functional meth addicts" like there are with "functional alcoholics" wow look there I go, with my nomenclature argument. Take any reward system drug like opioids or cocaine a few times and you're hooked. With alcohol, it isn't even close to that. Alcohol is not the most powerful drug.
My last point: alcohol changes you into another person. Meth makes you cease to be human. There is a clear more powerful one here.