Think about who has credentials that might allow a 2:22 or better quality race:
Kastor, has run 2:19, has a OG bronze run with a very competitive last 10k
Goucher: her 1/2 PR is almost WR level on an only modestly downhill course and has run pretty well in a couple of WRM. Also has a medal
Flanagan: Has run world-class races (Bronze WXC) and has great range, a high WMM finish with a modest time but against top runners and with a hard-paced last 10K.
A little thinner in terms of a really top single marks but with something close:
Desi: her WMM placing and nature of her finish and time.
What do runners do if either immediately or after a bit Kastor takes off at 5:20 pace. She may never come back. Now it is the trials and they might figure if she can hold that pace she would be on the team no matter what they did and then hope she blows up. I see her possibly doing this if the pace is too much slower than 5:35 pace. However, I also see her thinking that if they let her get through the first half without blowing her fuel out that she might then rely on that world-class background that is not quite there for a full race at pace but can stitch a 5:20 finish on to a 5:40 start. Flanagan can probably count on going with any strategy in the sense of letting someone with a very hard pace go and figuring she can run the last 10K with anyone.
I am not saying any of those first three is a lock but that they each have an advantage because the other runners know that they have done things that are beyond them (except maybe not beyond Desi). No one other than those four is likely capable of running a 2:22-quality race [caveat, the new Kenyan-born American might have that level, I do not know enough about her].