Daily 35 minute runs for a total of 245 minutes all runs were barefoot on the sand dunes.
16:33 progression using HR from 65 to 80 percent effort hr 156 on sand dune
Ridge dunes 8:50 out 7:43 back 16:33
23andme and promethease extremely interesting but not for the everyone.
Lots of data on various SNPs(single nucleotide polymorphisms)
caveat emptor
DNA sequencing ran thru the SNP database. It is just something that I did and found interesting and useful in many ways.
Example matches using promethease from my DNA:
s17602729(T;T)
AMPD1 deficiency homozygous This is found in ~2% of all caucasians. The majority of people with the AMPD gene are asymptomatic, but in response to vigorous exercise, others have symptoms including early fatigue, muscle pain and muscle cramping.
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http://en.wikipedia.org/wiki/Adenosine_Monophosphate_Deaminase_Deficiency_type_1
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http://rarediseases.info.nih.gov/GARD/Condition/547/QnA/23731/Adenosine_monophosphate_deaminase_1_deficiency.aspx
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http://www.ncbi.nlm.nih.gov/clinvar/RCV000019933.1/
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http://evidence.personalgenomes.org/AMPD1-Q12X
This position is odd. Under the older reference genome build36, it was on the plus strand; in build37 it is on the minus strand. This makes it very prone to some ambiguous flip confusion in the literature, plus, 23andMe users have self-reported the flipped form. IN addition, instead of the usual SNP listed as having 2 alleles, all 4 alleles are reported in dbSNP, even if this is probably due to the strand changes. dbSNP currently says the normal allele is C, and T is the rare geno which causes a premature stop, early in the gene. We at SNPedia suspect that the A & G alleles are not common enough to have ever been genuinely reported, but for de-novo mutations each allele would be non-synonymous and result in a different amino acid.
http://snpedia.blogspot.com/2012/12/snpedias-nightmare-before-christmas.html
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Bad Repute
3 Magnitude
2.7% Frequency
rs1815739(C;C)
Better performing muscles. Likely sprinter. This genotype indicates better performing muscles, particularly for sprinting and power sports. Fast-twitch muscle fibers are able to produce alpha-actinin-3. Professional sprinters usually have this, although it is less common for endurance athletes.
This SNP, in the ACTN3 gene, encodes a premature stop codon in a muscle protein called alpha-actinin-3. The polymorphism alters position 577 of the alpha-actinin-3 protein. In publications the (C;C) genotype is often called RR, whereas the (T;T) genotype is often called XX. According to (T;T) is under-represented in elite strength athletes, consistent with previous reports indicating that alpha-actinin-3 deficiency appears to impair muscle performance. However in 2016 failed to replicate casting some doubt. The most common nucleotide at this position, (C), encodes an arginine (amino acid code R), the alternative T allele encodes a stop codon (X). Hence, the SNP is referred to as R577X, with homozygotes being either RR or XX and heterozygotes being RX. XX individuals completely lack the expression of alpha-actinin-3. One of the earliest report studying a relatively small number of Australian elite (i.e. ~Olympic) athletes found that, at least in females, the R allele (ie...
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Good Repute
2.2 Magnitude
19.5% Frequency
