I have no clue why, but about 45 minutes into my hour run today, my right ankle started to hurt. I was able to make it home, and once I took my shoes off, I was fine. I wear Nike Air Pegasus 27's. Then, I went to put them on to go take out the trash really quickly, and the pain came back just by walking in them. I took them off again, and didn't have the pain again for about 4 hours until I tried them on a third time. Again, it hurt, but this time it almost hurt just to simply have them on while sitting down. It's just the weirdest thing. I've never had problems with the shoe before, comfortably logging 50+ mile weeks without any injuries. But now I just cannot wear them. Can anyone make some sense out of this? I would really like to keep wearing them, and I just want to know what the hell is going on.