Most people living in colder climates are Vit D deficient, at least during the winter months, and especially if the person has darker skin. Vit D is important in proper immune function, which partially explains why people tend to get sick in the winter. Vit D is lipid soluble (you don't just pee it out) and thus there has been concern for toxicity due to buildup, but so far there is no evidence of toxicity from Vit D supplements, even at high doses. Most Vit D supplements provide around 1000 IUs; considering standing out in the sun in shorts for half an hour provides over 10,000 IUs, it's unlikely anyone will overdose from a vit D supplement. Those who are deficient sometimes take as much as 25,000 IUs a day until their levels return to the normal range.
Vit D supplements are almost certainly unnecessary for anyone who spends a significant amount of time outdoors with a fair amount of skin exposed, but is almost certainly beneficial for those living in cold climates during the winter months.
Just some anecdotal evidence, I was feeling pretty crappy on runs for about 3 weeks, started taking vit D and started to feel better on my runs about two days later. I didn't actually have my levels checked, and I can't say it wasn't something else, but given what I know I'm going to keep taking the supplements until spring.