Over the past 15 years I've had a few MTP joint issues including distal metatarsal fractures of the 2nd Met.
Problems that involve this part of the foot relate to the foot anatomy and shoe design. Having a Morton's Toe whereby the 2nd toe is longer than the 1st predisposes one injuries to the 2nd Met.
In my experience, shoes that are very flexible in the forefoot while also employing non-supercritical EVA midsoles invite injury of the MTP joint for those predisposed to them. Orthotics can also contribute to the MTP loading problem by shifting it to the other lateral Mets. In my own experiments I ended up causing excessive edema in my lateral Mets through the use of aftermarket Orthotic insoles. I'm in agreement with the consensus view among foot and ankle orthopedic specialists that current clinical research has shown little or contradictory evidence that either stability shoes and orthotics prevent injuries in runners.
My MTP issues are now in the past. But if I was dealing with an inflammatory issue or coming back from an injury I would use shoes such as the HOKA Mach or the Asics GlideRide for their protective benefits.