(Her doctors would choose the drug that works for her condition, not her running… as a side response to “there are other drugs she could take that don’t need a TUE”).
America doesn't exactly have a shortage of quack doctors all too happy to give you PEDs
Huge fan but I noticed Molly's issues a while ago. Though she is well rounded, she had somewhat of a socially dormant experience as a teenager. Then wham, bronze medal, Time, Espn and Newsweek along with 229k followers instagram.
This got to her. Exposure to alcohol got to her. Caffeine got to her. Adderrall has gotten to her.
Whatever underlying mental problems were there are now on the surface.
But this post will get downvoted for noticing.
Ah the John Mayer affect.
Sudden stardom like winning the lottery. Wish her the best but when fame happens everything comes to the surface and you try to be more when you don’t.
Both Adderall and Adderall XR have elimination half lives of 9-14 hours. That means that once you stop taking it, assuming you had taken it long enough to reach “steady state”, every 9-14 hours you would clear half of it. VERY GENERALLY speaking, it would take 5 half lives to be out of your system by 97%. So she would have to stop taking it 45-70 hours before a competition to be off of it “in competition”… so about 3 days. I don’t think most mental health professionals would think that’s a safe way to treat a medical condition. It would take another 5 half lives when she’s back on it to get to therapeutic steady state again. See-sawing on and off a drug is never good medicine, hence the application for TUE.
(Her doctors would choose the drug that works for her condition, not her running… as a side response to “there are other drugs she could take that don’t need a TUE”).
My psychiatrist literally encourages me to not take adderall on the weekends to give myself a break and not build up tolerance. Its probably a matter of not wanting to risk getting off it for 3 days and it potentially still showing up in a test as that would still be a positive test. Not saying this in a mean way but if she can’t be off adderall for 3 days (which I don’t think is the case) then she has much larger issues. It’s not an antidepressant that takes time to take affect and going off it resets that. It’s honestly pretty baffling with how infrequently she races that she wouldn’t just stop taking it the week before and be 100% confident that it’d be out of her system
100% agree. After NYC I made some comment on here about Molly’s meteoric rise to stardom, calling it suspicious. I don’t think that she is on PED’s, I think that she probably started cutting some corners with nutrition, slimmed down and lost some weight, which led her to have an incredible year or so, and then the consequences came home to roost
100% agree. After NYC I made some comment on here about Molly’s meteoric rise to stardom, calling it suspicious. I don’t think that she is on PED’s, I think that she probably started cutting some corners with nutrition, slimmed down and lost some weight, which led her to have an incredible year or so, and then the consequences came home to roost
I think running 130 mpw it's probably hard to get in enough calories even if you aren't consciously taking shortcuts with nutrition. Add being on adderall on top of that (which majorly suppresses appetite), and that could be a recipe for underfuelling and poor recovery.
The key here is amines. There are ADD drugs like Vyvanse that are not amphetamines. Sympathomimetic amines are not amphetamines and are considered to be a new class of drug to fight ADD.
I thought the keyhere is Sympathomimetic. Sympathomimetic drugs are also known as adrenergic drugs and adrenergic amines.
??? Vyvanse is in the amphetamine class??? Not sure if you are trying to be obtuse?
Our findings represent the most comprehensive available evidence base to inform patients, families, clinicians, guideline developers, and policymakers on the choice of ADHD medications across age groups. Taking into account b...
There are ADD drugs like Vyvanse that are not amphetamines.
TL;DNR: Vyvanse pills are not amphetamines. but Vyvanse is made from amphetamines, and Vyvanse turns into amphetamines in the body.
Bottom line:Vyvanse has the same effects on the body as (other) amphetamines.
For those who are not up on their pharmacology, Vyvanse is what is called a pro-drug. Pro-drugs are made by attaching other molecules to drug molecules. The goal is to improve the delivery of the drug.
Vyvanse is made by attaching a lysine molecule to a dextroamphetamine molecule. When Vyvanse hits the bloodstream, the lysine is detached, and the Vyvanse is converted into dextroamphetamine.
Vyvanse has several benefits over regular d-amp. First, dosage control: Because of the attached lysine, the uptake of Vyvanse varies less with conditions in the gi tract. Second, and more importantly, because of the dynamics of the lysine cleavage, the d-amp from Vyvanse is delivered over an extended period, and more smoothly. The extended release means longer and more consistent control of ADHD symptoms, and reduces the potential for abuse.
I did include a link for a journal article that deals with this in an earlier post, but for reasons that I will never understand, the post was deleted because ‘I attacked another poster.’ Thanks for clearing it up though.
queen_bee: Please see #128 below. Amphetamines can be abused in more ways than drugs like Vyvanse - also VV has the potential for efficient time release. There are numerous other drugs in the pipeline. Just surprised that you weren’t aware of them - that’s hardly obtuse.
100% agree. After NYC I made some comment on here about Molly’s meteoric rise to stardom, calling it suspicious. I don’t think that she is on PED’s, I think that she probably started cutting some corners with nutrition, slimmed down and lost some weight, which led her to have an incredible year or so, and then the consequences came home to roost
I think running 130 mpw it's probably hard to get in enough calories even if you aren't consciously taking shortcuts with nutrition. Add being on adderall on top of that (which majorly suppresses appetite), and that could be a recipe for underfuelling and poor recovery.
^It’s this. Molly is falling into the same pattern that she did at the end of her college career. She is competitive as hell AND is OCD. That’s a bad combination for an endurance athlete as she is running herself into the ground and then not eating or sleeping well enough to bounce back from it. She needs to remember what got her to Tokyo, and that was just enjoying her running. The problem for Molly is that it’s really hard for her to be content with an Olympic bronze and being pretty good. She wants to be the best, and it’s literally harming her right now.
Hope she's able to get healthy, make a good recovery, and sort out the TUE questions. She's fun to watch and the sport is better with her in it
The TUE questions should take care of itself if Molly gets herself right again. Nobody needs to be on Adderall, but they grow to depend on it if other things aren’t going right.
Hope she's able to get healthy, make a good recovery, and sort out the TUE questions. She's fun to watch and the sport is better with her in it
The TUE questions should take care of itself if Molly gets herself right again. Nobody needs to be on Adderall, but they grow to depend on it if other things aren’t going right.
This may be unpopular- but I agree nobody needs to be on Adderall. Especially not a pro runner.
At first I thought it was just a regular old TUE but it is suspicious how hard they are fighting over something you don't need.
Non-runners who could GAF about running, long distances especially, are asking me advice about their first 5k after seeing her run in the August heat last year. Dormant runners I know are getting back into the sport now because of her bronze. It's a ripple effect.
I get what you are saying in terms of being exposed to things too much too fast, but Molly (even if she's flawed, as we all are) has made such an impact on our sport in such a short time. I'm pulling for her!
I want to echo your comments. My daughters are good D3 collegiate distance runners, so they are not future pros or anything, but they care about and follow the sport. There is no doubt Molly is the major role model to them and their teammates in a way that Cranny or Schweizer or even Touhy are not. Molly’s success, coupled with her public demeanor, and her very public struggles in areas that affect many of the young women, make her highly relatable and inspiring. My daughter’s are well aware of the members of our wc distance team, but nobody else moves the needle for them like Molly with the possible exception of Mu.
You do know that stimulants are only prohibited "in competition," right?
Some amount of the stimulant caffeine is allowed. The question remains as to how much this drug boosts performance, and should a TUE be allowed, per those claiming it doesn’t positively affect performance. If it stimulates greater heart contractions, I could foresee someone wanting it in their drink bottle in the later stages of a marathon if it could result in a pay-day, regardless of any long term detrimental consequences to its use.
I'm toying with caffeine the day of the race; it doesn't seem banned in Columbus Marathon's guidelines.
I think running 130 mpw it's probably hard to get in enough calories even if you aren't consciously taking shortcuts with nutrition. Add being on adderall on top of that (which majorly suppresses appetite), and that could be a recipe for underfuelling and poor recovery.
^It’s this. Molly is falling into the same pattern that she did at the end of her college career. She is competitive as hell AND is OCD. That’s a bad combination for an endurance athlete as she is running herself into the ground and then not eating or sleeping well enough to bounce back from it. She needs to remember what got her to Tokyo, and that was just enjoying her running. The problem for Molly is that it’s really hard for her to be content with an Olympic bronze and being pretty good. She wants to be the best, and it’s literally harming her right now.
I have a bit of OCD and anxiety myself, running calms me. But I am competitive and hard on myself too. So your post really hit home with me and (I don't know if it's true with Molly, though) at least makes logical sense.
queen_bee: Please see #128 below. Amphetamines can be abused in more ways than drugs like Vyvanse - also VV has the potential for efficient time release. There are numerous other drugs in the pipeline. Just surprised that you weren’t aware of them - that’s hardly obtuse.
Sigh, alright man. I am not arguing Vyvanse has less abuse potential- I think it’s a great medication. I’m simply stating that amphetamines have the best evidence for adults in the current literature per the article I cited, and included Vyvanse in that grouping.
You keep on referencing these “drugs in the pipeline” but have not named them. Are you talking about modafinil? Which is off label for adult ADHD? Or other experimental drugs that would be harder to get a TUE for? Pray tell.
You keep on referencing these “drugs in the pipeline” but have not named them. Are you talking about modafinil? Which is off label for adult ADHD? Or other experimental drugs that would be harder to get a TUE for? Pray tell.
Repeat after me, VV is not an amphetamine. Modafinil is old news.
If you are a psychiatrist, I feel sorry for your clients. You appear to be ignorant or disingenuous or possibly both. There are many prodrugs currently in clinical trials - is that pipeline enough for you? Do you need some help with looking things up in https://www.clinicaltrials.gov/ ?
Azstarys Is one example. It was FDA approved in 2021 for the treatment of kids and adults. You want some more?
