Primo Numero Uno wrote:
2600 bro wrote:
How big was the Polio vaccine Ph3 trial? What were the endpoints? Adverse event rates?
You see where I’m going :)
Not really. The polio vaccine issue had nothing to do with trials and was a manufacturing error. I was merely pointing out the irony of using a disastrous vaccine rollout as a jumping-off point to tell people they should get the Covid vaccine. Where did you think you were going?
The COVID vaccine rollout has been extremely safe. The primary issue has been lack of supply and distribution worldwide.
Safe to say, manufacturing, QA, and QC protocols are substantially better than they were 70 years ago.
The contamination issue in Japan, for example, was caught very quickly.
Also characterizing the polio vaccine rollout as disastrous is hyperbole as 3000 kids died of polio in 1952. 10 died from the bad batch of the vaccine. The error was tragic yet thousands of lives were saved within a year or two of the vaccines distribution. People widely recognized the risk:reward of the vaccine was still very, very high even after the bad-batch incident. (The calculus for the covid vaccine is similar... very good risk:reward ratio.)
So yeah, I think it's a decent comparison. Even with a tragic mishap, the populace didn't give into fearmongers, continued vaccination, and saved tens of thousands of lives.