I received dose one of the Pfizer vaccine. AMA.

trashcan wrote:

reading posts on let’srun also produces unpredictable methylation of the dna used in cells throughout our body.

Btw methylation isn’t like flipping a switch, more like turning a dimmer up or down.

Do you have a particularly concerning mechanism by which this occurs, or is it more along the lines of “any novel experience or exposure will produce unpredictable methylation changes.” And sources please, definitely better if peer-reviewed.

Kind of along the lines that shooting poison into my body that will almost certainly make me rather sick right away may have long term consequences. Source? Common sense

Snord wax buff wrote:

runner_hero wrote:

We’re not sure if it prevents transmission or not. Hypothetically it should but this hasn’t been proven or disproven yet. I partially got it on the hope it can prevent transmission. And if it doesn’t prevent transmission, then it’s kind of checkmate, virus wins.

I doesn't prevent transmission may lower the R0.

More importantly, what is now becoming clear, is that it does not immunize against the various mutants, and separate vaccines will be needed for those when they become available. This is all going to end up like flu shots, where every winter, the medical profession comes up with a different cocktail that 30-40% of the public will go get with very speculative results. For most people that issue will be: "is this worth the hassle again this year?"

At some point that will be true, the question is how long will it take. All viruses mutate, but Covid appears to mutate slower than influenza. Here is the best data I have found.

If anyone has a closer comparable in terms of mutation rate, that would be interesting.

And we definitely cannot say it DOESN’T protect against the various mutants. Given its mutation rate (slow-ish) we would predict that it DOES protect against any mutants that arise over the course of a year. Of course any concerning mutations should be checked.

Again if you found a virus with a vaccine that has a closer mutation rate than influenza, you could get a better prediction of the durability of benefits of the vaccine.

[quote]trashcan wrote:

reading posts on let’srun also produces unpredictable methylation of the dna used in cells throughout our body.

Btw methylation isn’t like flipping a switch, more like turning a dimmer up or down.

https://www.youtube.com/watch?v=Ges2yk2PNcA&feature=share&fbclid=IwAR0h_PZ7beXoq9AMYsI7RbuWi7YU4p2D-AxMLq-ueG3b9fclEKn55Nh8tOU

The Unkle wrote:

There was basically NO flu season in the Southern Hemipshere this past flu season (ended a few months ago south of the equator). Flu was down 98%

And the same thing is going on in America and the rest of the Northern Hemisphere in the current flu season. Despite this, there is a big push on for the flu vaccine this year with MA requiring kids to get a flu shot to attend school to avoid a "twindemic".

This is the case in both states with mask mandates and lockdowns and those without.

Where did the flu disappear to?

It’s still out there just much less prevalent.

runner_hero wrote:

The Unkle wrote:

There was basically NO flu season in the Southern Hemipshere this past flu season (ended a few months ago south of the equator). Flu was down 98%

And the same thing is going on in America and the rest of the Northern Hemisphere in the current flu season. Despite this, there is a big push on for the flu vaccine this year with MA requiring kids to get a flu shot to attend school to avoid a "twindemic".

This is the case in both states with mask mandates and lockdowns and those without.

Where did the flu disappear to?

It’s still out there just much less prevalent.

Yes. I think a 98% drop in flu cases qualifies as much less prevalent.

Where did it go? The same decrease applies in states and nations that did not require masks everywhere and did not lockdown so much as in those that did.

Bad Wigins wrote:

runner_hero wrote:

Mild myalgia (muscle soreness) of my left deltoid for two days. Otherwise none that I’m aware of.

unpredictable methylation of the DNA used in the cells invaded and coopted by the mRNA in the vaccine, the random flipping thereby of genetic switches related to cancer risk, and the persistence of this methylation through many cell divisions isn't necessarily something you'd notice right away.

Post again in 10 years and say if you've got cancer or not.

Or the OP can post again in 10 years to say if he has Creutzfeldt-Jakob disease caused by an abnormal protein.

The Unkle wrote:

runner_hero wrote:

It’s still out there just much less prevalent.

Yes. I think a 98% drop in flu cases qualifies as much less prevalent.

Where did it go? The same decrease applies in states and nations that did not require masks everywhere and did not lockdown so much as in those that did.

The flu virus is still circulating among its host organisms, humans included, but is much less prevalent this year possibly because of coronavirus restrictions.

runner_hero wrote:

The Unkle wrote:

Yes. I think a 98% drop in flu cases qualifies as much less prevalent.

Where did it go? The same decrease applies in states and nations that did not require masks everywhere and did not lockdown so much as in those that did.

The flu virus is still circulating among its host organisms, humans included, but is much less prevalent this year possibly because of coronavirus restrictions.

As noted, down 98% -- across the board including nations and states that did not force heavy coronavirus restrictions (that don't seem to work on Covid in any event).

Bump. How was your second dose? I got my first shot yesterday and my only side effect has been slight soreness in my deltoid. But I’ve heard the second dose is worse?