Study Showing That Hydroxychloroquine Reduces COVID Deaths by Half

"all these doctors and scientist ran DELIBERATELY ran their trials WRONG to make Trump look bad"

Where is the conservative-funded RCT finally prove all the HCQ-bros right? If it's so obvious it should be easy to get gold-standard data, no?

You missed the part where he states that most studies gave the medication to patients at too late of a time to be effective, which is true.

A lot of the studies being referenced as saying it doesn't work actually say the opposite. The study will say for patients at this point hydroxychloroquine is not an effective treatment, however, it can be effective if ......

The problem is people either do not read the entire study. The media also is trying to get clicks, not educate the public. They publish with a headline about how it does not work. But if you read down in paragraph 20, which no one gets to, it will say how the drug is shown to positive impacts in .........

There has absolutely been a politicized war on truth throughout the virus. Hydroxychloroquine is not a cure-all and in many cases it is useless. But there is mounting clinical evidence that it can be beneficial.

If it works why are foreign countries not using it?

Are they in on the hoax to make trump look bad?

The Predictor wrote:

You missed the part where he states that most studies gave the medication to patients at too late of a time to be effective, which is true.

No I didn't lol. If this was all obvious there would be RCTs to prove it. Somehow every RCT has just missed the obvious timing/dosing/whatever to show a clear effect. How unlucky!!

Your'e being logical. Trump supporters give unfettered fealty to their leader, logic does not work with them. Every discussion descends into rah rah rah about fake news and leftists.

Well duh. RCT gets random people to be tested on. That could include those who will die in 5 minutes or those who weren't going to die either way. For it not to be a RCT, you would need to select a specific group of people to be subjects. If enough non-RCT studies were done, we would definitely know what works and what doesnt.

Anyone please correct me if I've miss-interpreted what an RCT is.

The Predictor wrote:

Well duh. RCT gets random people to be tested on. That could include those who will die in 5 minutes or those who weren't going to die either way. For it not to be a RCT, you would need to select a specific group of people to be subjects. If enough non-RCT studies were done, we would definitely know what works and what doesnt.

Anyone please correct me if I've miss-interpreted what an RCT is.

RCT means you randomize eligible participants into various control and treatment groups. You still can recruit specific people.

E.g. cancer therapeutic RCTs recruit patients with a specific cancer.

Primo Numero Uno wrote:

A lot of the studies being referenced as saying it doesn't work actually say the opposite. The study will say for patients at this point hydroxychloroquine is not an effective treatment, however, it can be effective if ......

The problem is people either do not read the entire study. The media also is trying to get clicks, not educate the public. They publish with a headline about how it does not work. But if you read down in paragraph 20, which no one gets to, it will say how the drug is shown to positive impacts in .........

What's more likely:

1) The authors of the study missed the fact that HCQ works and forgot to emphasize it in their manuscript

OR

2) You are mis-interpreting data due to confirmation bias

Thanks for the clarification. The idea I was trying to get across is that the patients should be separated in more specific groups in the studies and not just lumped together as a group of people who are all in the hospital for COVID. Example categories should be age, pre-existing conditions, estimated time 'til death, etc.

Maybe if enough studies like that come out we can rule out which groups triumph on x medication and which ones don't.

I frankly have no idea how difficult it would be to conduct these types of studies

I like that the best way to determine the efficacy of prescription drugs has been figured out on Letsrun. Thanks to all here for mansplaining what you the thousands of professionals worldwide who have generations of learnings, research and procedures could not put together themselves. The natural gift possessed by you guys is unmatched in the history of medicine.

The Predictor wrote:

Thanks for the clarification. The idea I was trying to get across is that the patients should be separated in more specific groups in the studies and not just lumped together as a group of people who are all in the hospital for COVID. Example categories should be age, pre-existing conditions, estimated time 'til death, etc.

Maybe if enough studies like that come out we can rule out which groups triumph on x medication and which ones don't.

Generally in a large enough trial it's feasible to do this.

You have to be careful analyzing too many subgroups looking for an effect. If every subcohort you analyze has a change of turning up a false positive, the more you look at the more likely you are to get one. This is often abused by people trying to show a positive effect for their dead-in-the-water drug.

Lots of statistical and methodological ways around this.

Generally it's very expensive to run an RCT, especially for 1000s of patients.

Gina wrote:

If it works why are foreign countries not using it?

Are they in on the hoax to make trump look bad?

Umm, there are foreign countries using it and they are having lower death rates. Use google and you find which countries do and don't use it. The one's who use it in the early stages of the virus(note: not in those hospitalized) have overall lower death rates. If you use it as intended it can help.

It's like saying providing water to someone dying of dehydration does not help because once all their internal organs have failed the water won't cure them. Sure but if you give them water at the initial stages of dehydration it will help them not get to the severe point. That is exactly the case for this medication. Once you're on a ventillator it won't help you.

THOUGHTSLEADER wrote:

I like that the best way to determine the efficacy of prescription drugs has been figured out on Letsrun. Thanks to all here for mansplaining what you the thousands of professionals worldwide who have generations of learnings, research and procedures could not put together themselves. The natural gift possessed by you guys is unmatched in the history of medicine.

????????????

Armstronglivs wrote:

https://www-sciencealert-com.cdn.ampproject.org/v/s/www.sciencealert.com/here-s-why-hydroxychloroquine-doesn-t-block-the-coronavirus-in-human-lung-cells/amp?amp_js_v=a2&amp_gsa=1&usqp=mq331AQFKAGwASA%3D#aoh=15970692463702&referrer=https%3A%2F%2Fwww.google.com&amp_tf=From%20%251%24s&ampshare=https%3A%2F%2Fwww.sciencealert.com%2Fhere-s-why-hydroxychloroquine-doesn-t-block-the-coronavirus-in-human-lung-cells

YOUR studies have been debunked, pal.

Primo Numero Uno wrote:

Umm, there are foreign countries using it and they are having lower death rates. Use google and you find which countries do and don't use it. The one's who use it in the early stages of the virus(note: not in those hospitalized) have overall lower death rates. If you use it as intended it can help.

It's like saying providing water to someone dying of dehydration does not help because once all their internal organs have failed the water won't cure them. Sure but if you give them water at the initial stages of dehydration it will help them not get to the severe point. That is exactly the case for this medication. Once you're on a ventillator it won't help you.

Are you descended directly from the line of Hippocrates? The insights you have discovered are earth-shattering and incredible.

There is a private jet to have you present and lecture in front of the WHO, CDC and world leaders on his prescription drugs and clinical trials work.

Exactly. Some of the states with the highest death tolls from Coronavirus had a ban on HCQ. Then they got desperate and finally allowed it's usage and things quickly got better.

Hundreds of thousands of doctors across the world, if not millions, are taking HCQ themselves as a prophylactic so they don't get COVID. Those doctors also continuously see dramatic improvements in patients at a certain stage who are given HCQ,

Liberals would rather see millions of people die than see Trump help just one person. It's sickening.

Another LRC'r uncovers a WORLDWIDE conspiracy to make Trump look bad.