Even here, Jono is absolutely wrong. It is absolutely true that faster runners tend to have higher absoluve VO2max and slower runners tend to ave lower absolute VO2max. That is pretty much the definition of correlation. (I know that you, test2, understand this already). If you get into a more nuanced argument, then you could of course say that that correlation is not determinative. Which would be true. if you tested a bunch of 16:00 5k runners, they could have results all over the place, and in that case the results would be down to efficiency. That just means the r value for it is not very good. If, on the other hand, you tested a bunch two groups, a bunch of 13 minute 5k runners and a group of 20 minute 5k runners, you would find that the faster runners, as a group, had a much higher absolute VO2max than the 20 minute runners.
He is of course right that improving efficiency is an important part of running. Maybe the most important part of it once you have some basic fitness. Of course if he posted that he couldn't have 20+ page threads full of arguing, since it is so blatantly obvious that nobody would disagree with it.
Of course you are right in the last statement, which is that if we agree that his entire argument boils down to this, and we granted that everything he said is correct, then it does nothing to prove that Performance Enhancing Drugs exist, or don't exist, or work, or don't work, etc.