Lots of times.
One that sticks out - I went to London and out for the evening with a date. We went out for a meal, and then to some kind of wine bar. My date got increasingly angry/possessive that I was talking to other people, and when we were talking in the outside garden threw a glass of wine at me which smashed against a wall that was behind me. I literally ran... I ran out of there, ran down the street, and ran streets and streets away until I went inside (which turned out to be an arcade). I don't know if I was followed but I did get away. I thought it was about to turn violent. I ran to my friend's flat in Waterloo. Being able to run in that situation made me feel a lot better. I just bolted.
The person contacted me after, phoning repeatedly, my friend took the phone call. 'Apparently' what had happened after was someone had seen the whole thing, came out of the bar and beat my date up. I didn't really know what to make of that, apart from I never wanted to see that person again.
I've used running as a mode of transport a lot.