aduck2022 wrote:
what idiot said cera gone out of system in days , weeks at least 40-50 days .last time i heard.
Hey...that was me! I was referencing Mørkeberg's paper; ~130-140 hrs for CERA:
http://m.asheducationbook.hematologylibrary.org/content/2013/1/627.long?view=long&pmid=24319242Also, CERA has a very similar molecular structure of 2nd gen Darbepoetin (NESP) which has a detection window of about a week. Remember this was the ESA that the gold medalist x3 in XC skiing (Johan?) tested hot for at the 2002 winter games.
https://www.researchgate.net/publication/6491772_Detection_window_of_Darbepoetin-a_following_one_single_subcutaneous_injectionOTOH, where did you hear CERA glows for "40-50 days?" Any references or anything? That wouldn't be much of a benefit for an athlete. For one, the OOC testing risk goes up exponentially and secondly, the athlete would have to stop 50 or so days before the targeted competition, which a lot of the benefits would be lost with a significant drop in Hct by then.
The hoopla and all with CERA being so popular with Ramzi & others was that they were led to believe that it was only detectable in plasma but not urine because it's excreted in very low concentrations. As long as they didn't give plasma for doping analysis they thought they were home free. If you remember Roche Labs assisted WADA is developing the detection methods for CERA from urine analysis.
Other than that there's really nothing that special about CERA. It stimulates RET% & raises Hct the same way that first gen EPO does...nothing new there. It was primarily deigned by Roche for dialysis patients providing more convenient once or twice a month injections that target desired Hct levels instead of 3 times a week injections with first gen EPO. Once or twice a month injections also made it more attractive to the dopers.