If you need to be on antidepressants, then that's the important thing, so maybe give it a shot.
My experience is that you lose all drive, which makes running, especially high mileage, rather difficult to say the least. You simply won't want to do it, and surprisingly, you won't really care much that your running is falling apart. Doesn't seem as important all of a sudden.
. And they're a b!tch to get off. The brain zaps are terrible. I've tried Effexor, Celexa, Lexapro, Zoloft, Luvox, Cymbalta, Wellbutrin..... I'm sure I'm forgetting some. Point is, I gave them a try and tried to be patient.
You might want to give some old-school ones a try that won't give you some of the side-effects that others (SSRI, SNRI) do, or are milder. I tried a SARI (Trazodone), which is an interesting drug. It will give you some sexual dysfunction to a degree, but not as much as the ones used today. Weight gain often doesn't occur. You likely will feel very sleepy on it at first, which goes away to some level, but a minor sedative effect will always be there, which is why it is prescribed off-label as a sleep aid in doses at a lower threshold than used for depression, and also is perfect for those with a depression/anxiety combo. There's also possibility of priapism, but it's not very common and usually only in larger doses.
One thing I liked about trazodone was the unbelievable dreams. Crazy, vivid, and the occasional ability to have a lucid dream experience, which can be worked on if you're into that, so you get better at controlling them. Once I looked up "trazodone dreams" on Google to see if I was the only one experiencing such amazingly vivid, awesome dreams. I quickly realized it's definitely a thing, and there's websites dedicated to people who take trazodone even though they don't need it, just in order to experience lucid dream states.