rekrunner wrote:
The knowledge we have for 2+ decades does not include much about elite distance runners. When you eliminate all these other non-running categories, and focus on male distance runners, you find a rather mediocre set of examples "in the field": some Spanish runners, and one Irish runner, performing at levels slightly better than pre-EPO European standards, being left far behind by Africans, and a handful of Moroccans. Or you find an aging Dutch master able to come close to his personal best 10 years earlier. Contrast that to cycling, where we have many examples of the best of the best and the best of the rest.
You mention Ferrari and Fuentes -- two doping doctors known to have worked successfully with many elite cyclists, and not known to have worked successfully with many elite runners.
I like the "Glasgow study" more than the cycling studies, because they actually measure running with time trials, and not just VO2max, or HcT, or cycling power, or TTE at 80% -- but that doesn't fix all the shortcomings, and has a few of its own.
You said "well trained" -- that doesn't seem to be the right way to describe these subjects, especially when the level of training, or the training load, wasn't assessed.
What would help? Rather than a short 6-18 week study on test subjects with random fitness, precede it with 600 weeks of competitive training by a competent coach, to first bring subjects close to their "clean" peak ability. Then we can measure if EPO brings an "unnatural" ability.
These subjects are still not elite, but this brings the subjects closer to the actual case of elite athletes able to produce elite times.
What else? Use all the data to build a model that shows EPO improvements, as a function of talent. Rather than compute an average for the group, show all the data, suggest a curve, or several curves, and show the correlation and measure of fit.
How would I apply the measures of the Glasgow study? If 11:20 3K Scottish runners improve 45 seconds, and 9:05 3K Kenyan runners improve 25 seconds, what can I say about Brahim Boulami, who ran a 7:38 3K and the 7:53 and 7:55 3K Steeple world records, times he can run thanks to many years of training which has brought him close to his peak abillity? What are his "clean" limits, and what are his EPO limits?
Regarding athletes like Gamze Bulut, it's optimistic to suggest she is a "clean" 4:18 runner. Although busted for ABP, we also haven't ruled out with any certainty that she did not take steroids. Therefore we cannot say with certainty that EPO caused a 17 second improvement.
Passport era wrote:That doesn't make sense...the knowledge that it's effective with endurance athletes has been around for 2+ decades or so. Doping doctors don't have a belief...they have knowledge or they wouldn't have been advising athletes on the usage of EPO & blood doping. Ferrari was obsessed with 02-vector doping...think he might know a little something about this? 🤔. And don't forget Fuentes with his blood doping clinic for dozens of athletes (a la Operation Puerto).
I agree...absent studies with elites, it's based on anecdotes, i.e., cycling, female distance runners, men's race walking, and men's distance running with the EPO positive test cases.
You didn't like the studies with EPO & amateur cyclists...you said the results wouldn't apply to runners, and you're now incredulous with the Glasgow study? The researchers said the Kenyans were "endurance trained," and granted their average 65 VO2max is nothing near elite status, it's not "hobby jogger" level either. Besides, these were altitude natives with above average baseline Hct's that showed a significant improvement in 3k time (~5%) that correlated with an increased VO2max from moderate dosing of rHuEPO (and yes...I know it's not blinded and small based, and all that, but that's the best there is right now).
Here's another paper showing increaed Hb/Hct improves VO2max and endurance capicity:
(link deleted)
Yes...the women mid-d runners are using steriods in a lot of doping positives. However, there are also cases where 02-vector doping has provided huge performance jumps. Take the most recent case of Gamze Bulut (1500 silver/London) just sanctioned for hematological anomalies on her ABP during that time period. She ran a PB of 4:01.18 in the semi's at London - up from her previous PB of 4:18.23 set in July of 2011. That's a mind-blowing 17 second (6%) improvement in 1 year! 😨.
On the off-scores, I'm getting the 133 from both the IAAF & UCI as the threshold needed for a passport sanction absent any other supporting evidence of doping (e.g., Shobukhova/153, Ugarova/141, Jonathan Tiernan-Locke/155).