You seem confident that you can do this without injury, but you're definitely putting yourself at higher risk and it might turn out that you're wrong. How much experience do you have running 100 mpw? If you have only done it for a couple weeks, then the fact that you haven't gotten hurt yet definitely doesn't mean that you can safely maintain this kind of volume.
My advice is to be a little more careful than it seems like you have to. Maybe do 90 instead of 100. Or if you really want to hit 100, maybe do weeks like 85, 90, 100, 85, 90, 100, etc. I'd try to avoid running above 90 two weeks in a row if you're accustomed to 80.
On the other hand, some people will definitely tell you to go for it, and just to be careful that a lot of the running is easy. I tried this, and it worked really well for me for about four months, HUGE prs, then I got hurt and got set way way back. Wish I had been just a tiny bit more careful. Then again, maybe you are more talented/resilient/whatever than I am and you could handle it. Since there's no way to really tell, I'd recommend being a little careful like I said above.