I am a Reno native, and although I live in Bangkok these days, I am proud of my hometown.
Reno has fine restaurants, a decent university, world class skiing nearby, excellent weather, and high altitude for runners like you and me. The weather never really gets too cold or too hot.
If you like sports, we have a fine university football team and basketball team worthy of your support. We also have a AAA Baseball team and a D-league NBA team.
If you like mountains or mountainous deserts for long runs or bike rides, you are well taken care of.
There is nothing depressing about Reno.
Financially, the nice thing about Neavada is no state income tax.