What is your education background, Lance? I only ask because though I agree with some of what you say, I kind of feel like you don't actually have much knowledge of what you're talking about. Brain disorders (and even brain function) isn't understood nearly as well as disease of the heart and other organs because it's much more difficult to study, not because it's inherently different from the rest of the body. The brain is encased in bone, animal models for diseases such as schizophrenia are difficult to impossible to create, and the brain and nervous system are incredibly complex. You also seem to use depression (along with anxiety probably the "disease" which is most overprescribed for) as a good representative for all mental disorders when it is not. I don't think you would be saying the things you are if you knew a little about the neurobiology of addiction, schizophrenia and bipolar disorder. Optogenetics is already drastically improving research into function within the CNS and will likely greatly improve our understanding of these disorders.
You seem to have an understanding of these things however when you say someone cannot talk their way out of brain cancer. I completely agree that drugs are the not the best answer for many (most?) people being treated for depression, and I think even most (nearly all?) psychiatrists would say environment plays a big role in a lot of these disorders, but there is a proven genetic component to many of these disorders as well, and even when people do everything they can to treat their illness, many still require medication. It is also incredibly ignorant to say medication provides no relief in any of these diseases. As someone who knows several people with mental disorders who have gone through medication changes, I find it almost laughable that anyone would think these drugs have no more effect than placebo. Perhaps in some disorders with certain groups of people, but to broaden that to all mental illnesses and all people is about as bonafide stupid and ignorant as one can get.
I honestly don't understand how anyone with a bit of knowledge of neurotransmitters, acion potentials, and ion channels could write something like the authors of this paper did, which is why I wanted some other people's opinions. I appreciate the responses.