Junk Master
Article for SprintGeezer 3/30/2012 1:47PM Reply | Return to Index | Report Post
http://www.slate.com/articles/sports/explainer/2012/03/justin_gatlin_is_sprinting_to_gold_again_is_it_possible_he_s_still_benefitting_from_doping_.html

On the long term benefits of juicing in light of Justin Gatlin's 60m championship.

I'd love to see a study done on epigenetic changes induced by PEDS.
Junk Master
RE: Article for SprintGeezer 3/30/2012 2:03PM - in reply to Junk Master Reply | Return to Index | Report Post
Delete this double post.
Sprintgeezer
RE: Article for SprintGeezer 3/30/2012 2:12PM - in reply to Junk Master Reply | Return to Index | Report Post
Junk Master--

Thanks for that link.

They don't really conclude anything, and chalk up the lack of knowledge to the fact that clinical trials would have difficulty getting approved.

But the question remains, and I think it's an interesting one--because if beneficial changes last a long time relative to current suspension lengths or to the length of a typical track career, a lifetime ban would be the only equitable solution.

Any new test would need either a baseline, or distinct evidence of past use, no matter when that use occurred.

If detected and use concluded, it would have to be investigated if the use had been for a legitimate therapeutic purpose, rather than for athletic advantage, such as could occur if somebody was voluntarily kept out of competition and totally ineligible from, say, 17-21 or 22 yrs of age, then released upon the scene while not currently using.

A fantasy, I know, but if the reward is big enough...

Thanks again for the link.
ventolin^3
RE: Article for SprintGeezer 3/30/2012 6:48PM - in reply to Junk Master Reply | Return to Index | Report Post
unsure why you are asking an obviously unscientific qualified chump for this ???

from a guy who does have some relevant qualification :

1) the "hypothetical" example is flawed :

he used to squat 500, injured 1y & says he squats 350 but back to 500 again quicker than a 350 guy trying to improve

the example is nonsense, as we have complete conjecture whether 1y is sufficient time for a 500 drop to 350 get back to 500

we are not expecting any specific musculoskeletal injury in this case such as a torn quadricep or herniated L5, but some insidious generalised illness which debilitates for 1y ?!

it may take YEARS to assuage the "insidiousness" for "non-surgical consideration maladies"

2) "epigenetics" ???

laughable proposition

we are not ameoboeic-organisms or even more pertinently bacteria/viruses which can adapt our genome within a few years of adverse/different conditions

it takes dozens of generations to develop genetic adaptations in erectus - look up malaria & sickle cell in africans

yes, i'm sure the heaviest dopers may develop some "epigenetic" changes thru pumping buckets of stanozolol for 10y into their blood, but once off, i doubt it woud have benefit after much than 4y, maybe a coupla hundredths over 100m

proof here :

the biggest doping bum came back to his

"mid/high-10.1 basic"

after 4y out with 2nd place

https://www.youtube.com/watch?v=z894i3LU_do
Sprintgeezer
RE: Article for SprintGeezer 3/30/2012 7:47PM - in reply to ventolin^3 Reply | Return to Index | Report Post
VenTurd--

You know exactly squat about 'roids or Johnson.

Johnson never could have run 10.1x without the benefit of 'roids. Ask me how I know.
toothpaste in my leg rub
RE: Article for SprintGeezer 3/30/2012 7:53PM - in reply to Sprintgeezer Reply | Return to Index | Report Post

Sprintgeezer wrote:

VenTurd--

You know exactly squat about 'roids or Johnson.

Johnson never could have run 10.1x without the benefit of 'roids. Ask me how I know.

OK "How I know?"
ventolin^3
RE: Article for SprintGeezer 3/30/2012 8:31PM - in reply to Sprintgeezer Reply | Return to Index | Report Post

Sprintgeezer wrote:

VenTurd--

You know exactly squat about 'roids or Johnson.

Johnson never could have run 10.1x without the benefit of 'roids. Ask me how I know.


f*ckin! moron

he was a 6.5+++ basic who didn't last to 100

same as your peabrain can't transpose to cason with 6.41i not running 9.82 basic off that & ~ 9.75 with good wind, but went 9.92 with 0.3

get it into your numbskull

he was a 6.5+++ who didn't last the last 40m even stuffed to the gills with stanozolol, proofed, as his seoul 6.33 split indicated

9.66

but even without celebrating, he wasn't going to run better than mid-9.7

with the 1.1 wind which gave him

0.05 - 0.06
powergeezer
RE: Article for SprintGeezer 3/30/2012 8:52PM - in reply to ventolin^3 Reply | Return to Index | Report Post
The article isn't great.
A 500 lb squat comes back more quickly because the person has the ability to do it in the first place. They also have the confidence, determination and experience that it takes.

Re steroids: Within 6 months you are fully back to normal (if not worse due to suppression). The fact that certain compounds are detectable for longer periods, doesn't mean that they are present in effective doses.

The only advantage that former dopers have is the type of competitive mindset that got them there initially.
Anonymous Intent
RE: Article for SprintGeezer 3/30/2012 8:56PM - in reply to ventolin^3 Reply | Return to Index | Report Post
Another interesting thread derailed by the narcissistic Ventolin.
Junk Master
RE: Article for SprintGeezer 3/30/2012 10:57PM - in reply to ventolin^3 Reply | Return to Index | Report Post
"we are not ameoboeic-organisms or even more pertinently bacteria/viruses which can adapt our genome within a few years of adverse/different conditions

it takes dozens of generations to develop genetic adaptations in erectus - look up malaria & sickle cell in africans"

But if the genetic adaptations ALREADY EXIST and are just being activated it can take as little as TWO WEEKS.

Ventolin, I'm shocked you are so far behind current gene expression theory.

Lots of pathways that can be switched on and off due to various exogenous stimuli.

Take cold adaptation for example.
Junk Master
RE: Article for SprintGeezer 3/30/2012 11:08PM - in reply to Junk Master Reply | Return to Index | Report Post
What I'm most interested in, and the article doesn't address, is anyone who has firsthand experience with PEDS, which I have from my weight lifting days (albeit in a minor way compared to most), is the response to PEDS is so genetically controlled.

Some people do one cycle and BLOW UP. There are clearly hyper-responders.

I'm sure the same is true with EPO, though I have no experience with that substance.

The fact that Coach Canato insists Kenyans don't benefit tells me they must benefit LESS that Eastern Europeans or Chinese-- who clearly do.

Not to mention, the whole subject of epigenetic changes triggering hyper-response in the offspring of PED users has yet to be touched upon.

I'd bet kids of PED users, if they were using before conception (of course) have a more significant response to PEDS.

Therefore kids of PED users will get a bigger advantage from using PEDS.

When that is proven, remember you read it here first-- and it wasn't Ventolin who posited it.
ventolin^3
RE: Article for SprintGeezer 3/30/2012 11:40PM - in reply to Junk Master Reply | Return to Index | Report Post

But if the genetic adaptations ALREADY EXIST and are just being activated it can take as little as TWO WEEKS


super-mouse ??


Ventolin, I'm shocked you are so far behind current gene expression theory


it works only on embryonic level

science hasn't got there to modify a born rodent+


Lots of pathways that can be switched on and off due to various exogenous stimuli


impress me

offer prose not paste

when you offer sticking an injection into a 1'50 guy & show he runs 1'40 within 1/12, then come back...


Take cold adaptation for example


err...

cure for hypothermia ???
coach d
RE: Article for SprintGeezer 3/31/2012 12:19AM - in reply to Junk Master Reply | Return to Index | Report Post

Junk Master wrote:

http://www.slate.com/articles/sports/explainer/2012/03/justin_gatlin_is_sprinting_to_gold_again_is_it_possible_he_s_still_benefitting_from_doping_.html

On the long term benefits of juicing in light of Justin Gatlin's 60m championship.

I'd love to see a study done on epigenetic changes induced by PEDS.


The smoking gun:



A team of researchers has examined the impact of anabolic steroid use on power lifters years after the athletes had ceased to take the drugs. The researchers found that while physical traces of the drug no longer remained, changes in the shoulder and quadriceps still gave lifters an advantage years later.
http://www.sciencedaily.com/releases/2008/09/080925072430.htm



As usual, Eldrick runs his (foul) mouth off without having a clue. That's why Gary Hill banned him from T&FN, so he has infested letsrun.
0bi
RE: Article for SprintGeezer 3/31/2012 6:48AM - in reply to Junk Master Reply | Return to Index | Report Post
Interesting... anyone got more links?
Sprintgeezer
RE: Article for SprintGeezer 3/31/2012 11:52AM - in reply to coach d Reply | Return to Index | Report Post
d--

That's an interesting article. Although I've got too many things on my plate these days to investigate the research protocol and findings, it does at least suggest that there are some permanent, or at least long-term relative to an athletic career, structural changes in the body that are enabled by 'roids.

I have always believed this to be true. Take another PED, HGH--if administered at the right time in life, the effects are permanent, even if use is discontinued. I also believe that males don't physiologically, or biochemically, mature until they are around 30 or so, give or take a few years, and that any roid use prior to that time is somewhat analogous to giving HGH to a child, in that it can permanently alter structures and pathways that are still developing.

If true, it's not surprising. If the adverse side-effects can persist, and manifest later in life, I would suspect no reason that the same thing wouldn't apply to the "athletically positive", or anabolic effects.

Right now, reconciling the possibility of permanent advantages with temporary sanctions requires 1 of 2 things: either you decide that there ARE no permanent advantages and that hence the temporary sanctions are appropriate, or you just accept the wisdom of the policies underpinning the current sanctions.

I have done the latter. I don't want to stop watching worlds or OG's or nationals just because Gatlin or Chambers or whomever is competing, and to just declare all of track B.S. because of a potentially large deficiency in the protocol.

When I see a roided-up guy run incredibly fast, first and foremost what I see is an incredible athletic performance...only afterwards do I consider that it was bogus...but the performance stands. Heck, people still use videos of Koch, Johnson, etc. for training purposes.

So when I see a doper run, I see first and foremost an athletic performance--like Gatlin's sprint to win worlds--and using that metric, a sort of "addiction" to track, accepting the wisdom of the policies underpinning the current sanctions becomes not too difficult.

I think I'd feel differently if I were a competitor, however. Yeah, I competed against guys I knew were doping, massively. They were usually a bit older than me, the Johnson/McKoy/Issajenko era, so when I was young, I just assumed that they were intrinsically better than I was, because they were, say, 6, 7, or 8 years older...a big difference, even when you're 18, 19, or 20 (well, unless you're really great when really young like Lemaitre or Blake or Bolt, which I wasn't)--so even though there were issues, I didn't really care.

But if I were competitive with the very best, I'd probably be complaining like a bltch, like Lewis did about Johnson. I'd do everything possible within the rules to make his life crap, to try to take away some of the permanent advantage. I feel for the clean competitors today.

"Like who?", you ask? Well, there have got to be some...and if not, then even temporary sanctions are too long.
coach d
RE: Article for SprintGeezer 3/31/2012 12:24PM - in reply to Sprintgeezer Reply | Return to Index | Report Post
It appears that there's more. Up to now, I was only interested out of intellectual curiosity (if somebody dumped a box of sarms at my front door, I really wouldn't know what to do with it). But THIS is legal:



A majority of the research on creatine supplementation has focussed on its benefits for high intensity, short duration activities such as repeated sprint ability and short bouts of maximal activity. Recently creatine supplementation has been shown to dramatically increase muscular size and strength (Wilson, 1996, p.8). Balsom et al. (1992) proposed that the increase in body mass may be due in part to an increase in total body water content. However, they also suggested that part of the increase in mass may be due to an increase in the diameter of muscle fibers (Volek & Kraemer, 1996, p.206). Balsom et al. (1992) postulated that the increased volume of water within the muscle cells may act as a stimulus for protein synthesis (increased muscle mass) (Volek & Kraemer, 1996, p.206). This adaptation may be a more permanent adaptation than water retention, resulting in long term gains in lean body mass if training is continued.
http://www.qwa.org/articles/cre.asp



The evidence seems to argue quite strongly for a heavy loading period in the offseason/early season.